Literature DB >> 22785197

Investigation of false-positive results given by the QuantiFERON-TB Gold In-Tube assay.

Madeline Slater1, Julie Parsonnet, Niaz Banaei.   

Abstract

We investigated a sudden increase in the rate of positive QuantiFERON-TB Gold In-Tube results from 10% to 31% at a U.S. academic institution. Direct comparison of the TB antigen tubes with tubes from a different lot number identified that a potential problem with the TB antigen vials in a certain tube lot was the likely cause of the elevated positive rate. The underlying defect remains unknown. This finding warrants refinement of quality control programs by the manufacturer and users.

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Mesh：

Year:  2012        PMID： 22785197      PMCID： PMC3421800          DOI： 10.1128/JCM.00730-12

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  1 in total

1.  T-cell assays for the diagnosis of latent tuberculosis infection: moving the research agenda forward.

Authors:  Madhukar Pai; Keertan Dheda; Jane Cunningham; Fabio Scano; Richard O'Brien
Journal:  Lancet Infect Dis       Date:  2007-06       Impact factor: 25.071
  1 in total
  20 in total

1.  Presumed tuberculosis-associated uveitis: rising incidence and widening criteria for diagnosis in a non-endemic area.

Authors:  N Krassas; J Wells; C Bell; M Woodhead; N Jones
Journal:  Eye (Lond)       Date:  2017-08-04       Impact factor: 3.775

2.  Challenges with QuantiFERON-TB Gold assay for large-scale, routine screening of U.S. healthcare workers.

Authors:  Madeline L Slater; Gary Welland; Madhukar Pai; Julie Parsonnet; Niaz Banaei
Journal:  Am J Respir Crit Care Med       Date:  2013-10-15       Impact factor: 21.405

3.  The dynamics of QuantiFERON-TB gold in-tube conversion and reversion in a cohort of South African adolescents.

Authors:  Jason R Andrews; Mark Hatherill; Hassan Mahomed; Willem A Hanekom; Monica Campo; Thomas R Hawn; Robin Wood; Thomas J Scriba
Journal:  Am J Respir Crit Care Med       Date:  2015-03-01       Impact factor: 21.405

4.  Caveats about QuantiFERON-TB gold in-tube testing for uveitis.

Authors:  Kathryn L Pepple; Russell Van Gelder; Farzin Forooghian
Journal:  Am J Ophthalmol       Date:  2014-04       Impact factor: 5.258

5.  False-positive quantiferon results at a large healthcare institution.

Authors:  Madeline Slater; Anthony Dubose; Niaz Banaei
Journal:  Clin Infect Dis       Date:  2014-03-06       Impact factor: 9.079

6.  Evaluation of Standard E TB-Feron Enzyme-Linked Immunosorbent Assay for Diagnosis of Latent Tuberculosis Infection in Health Care Workers.

Authors:  Oh Joo Kweon; Yong Kwan Lim; Hye Ryoun Kim; Tae-Hyoung Kim; Mi-Kyung Lee
Journal:  J Clin Microbiol       Date:  2019-11-22       Impact factor: 5.948

7.  Chronic lymphocytic meningitis with low CSF sugar, pulmonary infiltrate, and hilar lymphadenopathies in an immunocompetent patient.

Authors:  Raquel Vázquez-Picón; Marian Gómez-Beldarrain; Iñigo Vicente-Olabarria; Aida Rodríguez-Sainz; Juan Carlos García-Moncó
Journal:  Neurol Clin Pract       Date:  2015-08

Review 8.  Reproducibility of interferon gamma (IFN-γ) release Assays. A systematic review.

Authors:  Saloua Tagmouti; Madeline Slater; Andrea Benedetti; Sandra V Kik; Niaz Banaei; Adithya Cattamanchi; John Metcalfe; David Dowdy; Richard van Zyl Smit; Nandini Dendukuri; Madhukar Pai; Claudia Denkinger
Journal:  Ann Am Thorac Soc       Date:  2014-10

Review 9.  Gamma interferon release assays for detection of Mycobacterium tuberculosis infection.

Authors:  Madhukar Pai; Claudia M Denkinger; Sandra V Kik; Molebogeng X Rangaka; Alice Zwerling; Olivia Oxlade; John Z Metcalfe; Adithya Cattamanchi; David W Dowdy; Keertan Dheda; Niaz Banaei
Journal:  Clin Microbiol Rev       Date:  2014-01       Impact factor: 26.132

10.  Impact of blood volume, tube shaking, and incubation time on reproducibility of QuantiFERON-TB gold in-tube assay.

Authors:  Rajiv L Gaur; Madhukar Pai; Niaz Banaei
Journal:  J Clin Microbiol       Date:  2013-08-21       Impact factor: 5.948
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