Literature DB >> 22783375

Long-term survival after chemoembolization of metastatic right atrial tumor thrombus as a presenting feature of hepatocellular carcinoma: A case study.

Jun-Hui Sun1, Yue-Lin Zhang, Chun-Hui Nie, Li-Ming Chen, Jian-DI He, Wei-Lin Wang, Shu-Sen Zheng.   

Abstract

Advanced hepatocellular carcinoma (HCC) with invasion into the heart through the hepatic vein is a recognized rare occurrence with an extremely poor prognosis. Patients who present with right heart tumor thrombus have generally been considered inoperable. Although aggressive resection and liver transplantation treatment have previously been performed, the results remain unsatisfactory. However, HCC with extension into the heart usually indicates a contraindication for transcatheter arterial chemoembolization (TACE). In this study, a rare case of HCC with metastatic inferior vena cava (IVC) and right atrial (RA) tumor thrombus was reported. The young patient was admitted to our department due to Budd-Chiari syndrome. Following diagnosis according to CT image findings and laboratory data, the patient underwent TACE therapy. This treatment resulted in a marked reduction in the liver tumor and the right atrial tumor thrombus. Following TACE therapy, the patient survived for 3 years and 10 months and remains alive without any signs of recurrence. This case indicates that TACE therapy can be used successfully for the treatment of advanced HCC with heart tumor thrombus and may result in long-term survival.

Entities:  

Year:  2012        PMID: 22783375      PMCID: PMC3389639          DOI: 10.3892/ol.2012.618

Source DB:  PubMed          Journal:  Oncol Lett        ISSN: 1792-1074            Impact factor:   2.967


  21 in total

1.  Estimating the world cancer burden: Globocan 2000.

Authors:  D M Parkin; F Bray; J Ferlay; P Pisani
Journal:  Int J Cancer       Date:  2001-10-15       Impact factor: 7.396

2.  Growth of hepatocellular carcinoma into the right atrium. A case of antemortem diagnosis with magnetic resonance imaging of the heart.

Authors:  George Lazaros; Chrysoula Samara; Zoi Nikolakopoulou; Nicolaos Tassopoulos
Journal:  Acta Cardiol       Date:  2003-12       Impact factor: 1.718

3.  Hepatocellular carcinoma with intravascular and right atrial extension.

Authors:  Vui Heng Chong; Aza Zetty Fereona Jamaludin; Kian Soon Lim; Hj Md Syafiq Abdullah; Ramachandran T Nair
Journal:  Indian J Gastroenterol       Date:  2008 Nov-Dec

4.  Effectiveness of chemoembolization therapy for metastatic right atrial tumor thrombus associated with hepatocellular carcinoma.

Authors:  Y Dazai; T Katoh; I Katoh; S Sueda; R Yoshida
Journal:  Chest       Date:  1989-08       Impact factor: 9.410

Review 5.  Hepatocellular carcinoma and hepatitis C in the United States.

Authors:  Hashem B El-Serag
Journal:  Hepatology       Date:  2002-11       Impact factor: 17.425

6.  A successful treatment for hepatocellular carcinoma with atrial tumor thrombus.

Authors:  Y Kashima; M Miyazaki; T Kaiho; S Ambiru; A Togawa; M Ohtsuka; K Sasada; M Shiobara; Y Shimizu; S Yoshioka; H Yoshidome; H Omoto; A Katoh; S Nakamura; N Nakajima
Journal:  Hepatogastroenterology       Date:  1996 Jul-Aug

7.  Hepatic resection with tumor thrombectomy for hepatocellular carcinoma with tumor thrombi in the major vasculatures.

Authors:  T Asahara; T Itamoto; K Katayama; H Nakahara; H Hino; M Yano; E Ono; K Dohi; T Nakanishi; M Kitamoto; K Azuma; K Itoh; F Shimamoto
Journal:  Hepatogastroenterology       Date:  1999 May-Jun

8.  Hepatic resection for hepatocellular carcinoma.

Authors:  T Tsuzuki; A Sugioka; M Ueda; S Iida; T Kanai; H Yoshii; K Nakayasu
Journal:  Surgery       Date:  1990-05       Impact factor: 3.982

9.  Aggressive resection of hepatocellular carcinoma with right atrial involvement.

Authors:  Sander Florman; Michael Weaver; Paul Primeaux; Mary Killackey; Rafael Sierra; Santiago Gomez; Salima Haque; Fredric Regenstein; Luis Balart
Journal:  Am Surg       Date:  2009-11       Impact factor: 0.688

10.  Chemoembolization with cisplatin, lipiodol and Gelfoam and subsequent systemic chemotherapy with cisplatin and interferon in patients with hepatocellular carcinoma: a non-randomized prospective study.

Authors:  Martina Baur; Reinhard Walter; Axel Gebauer; Dimiter Tscholakoff; Herbert Lochs; Ferdinand Mühlbacher; Karl Turetschek; Reinhard Binder; Marcus Hudec; Alfred Gangl; Peter Ferenci; Christian Dittrich
Journal:  Int J Oncol       Date:  2003-09       Impact factor: 5.650

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  2 in total

1.  Progressive dyspnea and a right atrial mass in an 80-year-old man.

Authors:  Vera Demarchi Aiello; Ryan Yukimatsu Tanigawa; Rodrigo Caruso Chate; Fernando Peixoto Ferraz de Campos; Alfredo José Mansur
Journal:  Autops Case Rep       Date:  2019-11-27

2.  Surgical management of hepatocellular carcinoma with tumor thrombi in the inferior vena cava or right atrium.

Authors:  Kenji Wakayama; Toshiya Kamiyama; Hideki Yokoo; Tatsuhiko Kakisaka; Hirofumi Kamachi; Yosuke Tsuruga; Kazuaki Nakanishi; Tsuyoshi Shimamura; Satoru Todo; Akinobu Taketomi
Journal:  World J Surg Oncol       Date:  2013-10-05       Impact factor: 2.754

  2 in total

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