Literature DB >> 22782540

Microwave-assisted deacylation of unactivated amides using ammonium-salt-accelerated transamidation.

Yuhei Shimizu1, Hiroyuki Morimoto, Ming Zhang, Takashi Ohshima.   

Abstract

The combination of an ammonium salt and ethylenediamine promotes deacylation of a variety of unactivated amides to give the corresponding amines in high yields without the use of strong acids or bases. The reactions proceed without special care regarding air and moisture, and tolerate a wide range of functional groups.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID: 22782540     DOI: 10.1002/anie.201202354

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


  1 in total

1.  Simple and Economical Process for Producing Amantadine Hydrochloride.

Authors:  Phuong Dung Phan Thi; Tuan Anh Dang; Binh Duong Vu; Dinh Chau Phan
Journal:  ACS Omega       Date:  2022-02-04
  1 in total

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