Literature DB >> 227821

Initial United States clinical and pharmacologic evaluation of misonidazole (Ro-07-0582), an hypoxic cell radiosensitizer.

T H Wasserman, T L Phillips, R J Johnson, C J Gomer, G A Lawrence, W Sadee, R A Marques, V A Levin, G VanRaalte.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 227821     DOI： 10.1016/0360-3016(79)90061-0

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN： 0360-3016            Impact factor:   7.038


× No keyword cloud information.
  14 in total

1.  Dose-dependence and related studies on the pharmacokinetics of misonidazole and desmethylmisonidazole in mice.

Authors:  P Workman
Journal:  Cancer Chemother Pharmacol       Date:  1980       Impact factor: 3.333

2.  KIH-802, an acetohydroxamic acid derivative of 2-nitroimidazole, as a new potent hypoxic cell radiosensitizer: radiosensitizing activity, acute toxicity, and pharmacokinetics.

Authors:  K Sasai; Y Shibamoto; M Takahashi; L Zhou; H Hori; H Nagasawa; T Shibata; S Inayama; M Abe
Journal:  Cancer Chemother Pharmacol       Date:  1990       Impact factor: 3.333

3.  Structure-pharmacokinetic relationships for misonidazole analogues in mice.

Authors:  P Workman; J M Brown
Journal:  Cancer Chemother Pharmacol       Date:  1981       Impact factor: 3.333

4.  Enhancement of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) toxicity by acetohydroxamic acid analogues of 3-nitropyrazole in vitro.

Authors:  R T Mulcahy; D J Wustrow; R R Hark; A S Kende
Journal:  Invest New Drugs       Date:  1987       Impact factor: 3.850

5.  Effects of localised tumour hyperthermia on pimonidazole (Ro 03-8799) pharmacokinetics in mice.

Authors:  M I Walton; N M Bleehen; P Workman
Journal:  Br J Cancer       Date:  1989-05       Impact factor: 7.640

6.  Apoptosis and 1-methyl-2-nitroimidazole toxicity in CHO cells.

Authors:  C B Brezden; R A McClelland; A M Rauth
Journal:  Br J Cancer       Date:  1997       Impact factor: 7.640

7.  Sulphydryls, ascorbate and oxygen as modifiers of the toxicity and metabolism of misonidazole in vitro.

Authors:  Y C Taylor; A M Rauth
Journal:  Br J Cancer       Date:  1980-06       Impact factor: 7.640

8.  Radiation and nitroimidazoles in supratentorial high grade gliomas: a second clinical trial.

Authors:  R Urtasun; M L Feldstein; J Partington; H Tanasichuk; J D Miller; D B Russell; O Agboola; B Mielke
Journal:  Br J Cancer       Date:  1982-07       Impact factor: 7.640

9.  Effect of acute and chronic misonidazole administration on peripheral-nerve electrophysiology in mice.

Authors:  P J Conroy; R Von Burg; D P Penney; W Passalacqua; R M Sutherland
Journal:  Br J Cancer       Date:  1980-04       Impact factor: 7.640

10.  The role of dexamethasone in the modification of misonidazole pharmacokinetics.

Authors:  D H Jones; N M Bleehen; P Workman; M I Walton
Journal:  Br J Cancer       Date:  1983-10       Impact factor: 7.640
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.