INTRODUCTION: Considered as a neglected disease by the WHO, visceral leishmaniasis (VL) has expanded and urbanized. Its transmission and expansion have been linked to several factors. OBJECTIVE: To evaluate the epidemiological aspects of VL in the city of Aracaju/SE, through retrospective studies of the historical series of human and canine VL in the 1999-2008 period. METHODS: Secondary data from SINAN (Information System for Reportable Diseases) for human cases were used. Data from canine surveys and from the Zoonosis Control Center's (ZCC) passive demand were used for canine cases. RESULTS: 192 autochthonous cases of human VL were reported, and 63.5% were male. Children aged 1-4 years were the most affected (29.2%), followed by adults aged 20-29 years (15.6%) and children aged 5-9 years (15.1%). General mortality was 8.9%, and it was higher for the 60-69 year age group (60%); 32.3% of autochthonous cases performed serology for HIV, with a 6.9% positivity. Laboratory results were confirmed mostly by indirect isolated immunofluorescence (71.1%). 58,161 dogs were serologically tested for VL, with a positivity rate of 5.4%, while 87.0% of the surveys conducted annually by the ZCC, have a 4.4%positivity rate for VL. Of the 7,501 dogs that were brought to the ZCC for multiple complaints, the serological test was positive in 12.0%. CONCLUSION: Data show the endemicity of VL in the city, revealing the need for actions to reduce the risk of the population, mostly for the group with higher incidence and mortality, such as improvement in the diagnosis of VL and its HIV-associated infection, along with monitoring of the dog population, among others.
INTRODUCTION: Considered as a neglected disease by the WHO, visceral leishmaniasis (VL) has expanded and urbanized. Its transmission and expansion have been linked to several factors. OBJECTIVE: To evaluate the epidemiological aspects of VL in the city of Aracaju/SE, through retrospective studies of the historical series of human and canine VL in the 1999-2008 period. METHODS: Secondary data from SINAN (Information System for Reportable Diseases) for human cases were used. Data from canine surveys and from the Zoonosis Control Center's (ZCC) passive demand were used for canine cases. RESULTS: 192 autochthonous cases of human VL were reported, and 63.5% were male. Children aged 1-4 years were the most affected (29.2%), followed by adults aged 20-29 years (15.6%) and children aged 5-9 years (15.1%). General mortality was 8.9%, and it was higher for the 60-69 year age group (60%); 32.3% of autochthonous cases performed serology for HIV, with a 6.9% positivity. Laboratory results were confirmed mostly by indirect isolated immunofluorescence (71.1%). 58,161 dogs were serologically tested for VL, with a positivity rate of 5.4%, while 87.0% of the surveys conducted annually by the ZCC, have a 4.4%positivity rate for VL. Of the 7,501 dogs that were brought to the ZCC for multiple complaints, the serological test was positive in 12.0%. CONCLUSION: Data show the endemicity of VL in the city, revealing the need for actions to reduce the risk of the population, mostly for the group with higher incidence and mortality, such as improvement in the diagnosis of VL and its HIV-associated infection, along with monitoring of the dog population, among others.
Authors: Kellyn Kessiene de Sousa Cavalcante; Kelvia Maria Oliveira Borges; Francisco Roger Aguiar Cavalcante; Francisco Gustavo Silveira Correia; Caroline Mary Gurgel Dias Florêncio; Carlos Henrique Alencar Journal: Rev Soc Bras Med Trop Date: 2022-05-20 Impact factor: 2.141
Authors: Caique J N Ribeiro; Allan D Dos Santos; Shirley V M A Lima; Eliete R da Silva; Bianca V S Ribeiro; Andrezza M Duque; Marcus V S Peixoto; Priscila L Dos Santos; Iris M de Oliveira; Michael W Lipscomb; Karina C G M de Araújo; Tatiana R de Moura Journal: PLoS Negl Trop Dis Date: 2021-01-19
Authors: João Gabriel G Luz; Amanda G de Carvalho; João Victor L Dias; Luis Claudio L Marciano; Sake J de Vlas; Cor Jesus F Fontes; Luc E Coffeng Journal: PLoS Negl Trop Dis Date: 2021-10-08
Authors: Cláudia M Melo; Ana Carla F G Cruz; Antônio Fernando V A Lima; Luan R Silva; Rubens R Madi; Veronica de Lourdes S Jeraldo; Ruben Mercado Journal: Can J Infect Dis Med Microbiol Date: 2018-10-01 Impact factor: 2.471
Authors: Lucas Edel Donato; Lúcia Rolim Santana de Freitas; Elisabeth Carmen Duarte; Gustavo Adolfo Sierra Romero Journal: Rev Soc Bras Med Trop Date: 2020-09-11 Impact factor: 1.581