Literature DB >> 22781702

pH-triggered blooming of 'nano-flowers' for tumor intracellular drug delivery.

Zhefan Yuan1, Zhenyang Que, Sixue Cheng, Renxi Zhuo, Feng Li.   

Abstract

With the decrease in pH value, the 'nano-flower' exhibited a half-open state to expose the target ligands on the surface under tumor acidic conditions and fully bloomed to release Dox under endosomal acidic conditions.

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Year:  2012        PMID： 22781702     DOI： 10.1039/c2cc34225a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Hierarchical Targeting Strategy for Enhanced Tumor Tissue Accumulation/Retention and Cellular Internalization.

Authors:  Sheng Wang; Peng Huang; Xiaoyuan Chen
Journal:  Adv Mater       Date:  2016-06-03       Impact factor: 30.849

2.  A Smart pH-Sensitive Delivery System for Enhanced Anticancer Efficacy via Paclitaxel Endosomal Escape.

Authors:  Yihua Yang; Zhe Wang; Ying Peng; Jinsong Ding; Wenhu Zhou
Journal:  Front Pharmacol       Date:  2019-01-24       Impact factor: 5.810

3.  Metal-free trifluoromethylation of aromatic and heteroaromatic aldehydes and ketones.

Authors:  Yupu Qiao; Tuda Si; Ming-Hsiu Yang; Ryan A Altman
Journal:  J Org Chem       Date:  2014-07-15       Impact factor: 4.354
  3 in total

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