| Literature DB >> 22780913 |
Marthe T C Walvoort1, Anne Geert Volbeda, Niels R M Reintjens, Hans van den Elst, Obadiah J Plante, Herman S Overkleeft, Gijsbert A van der Marel, Jeroen D C Codée.
Abstract
Well-defined fragments of hyaluronic acid (HA) have been obtained through a fully automated solid-phase oligosaccharide synthesis. Disaccharide building blocks, featuring a disarmed glucuronic acid donor moiety and a di-tert-butylsilylidene-protected glucosamine part, were used in the rapid and efficient assembly of HA fragments up to the pentadecamer level, equipped with a conjugation-ready anomeric allyl function.Entities:
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Year: 2012 PMID: 22780913 DOI: 10.1021/ol301666n
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005