Literature DB >> 22779404

Total synthesis and complete stereostructure of gambieric acid A.

Haruhiko Fuwa1, Kazuya Ishigai, Keisuke Hashizume, Makoto Sasaki.   

Abstract

Total synthesis of gambieric acid A, a potent antifungal polycyclic ether metabolite, has been accomplished for the first time, which firmly established the complete stereostructure of this natural product.

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Year:  2012        PMID： 22779404     DOI： 10.1021/ja305864z

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  10 in total

1.  Stereoelectronic Model To Explain Highly Stereoselective Reactions of Seven-Membered-Ring Oxocarbenium-Ion Intermediates.

Authors:  Matthew G Beaver; Trixia M Buscagan; Olga Lavinda; K A Woerpel
Journal:  Angew Chem Int Ed Engl       Date:  2016-01-06       Impact factor: 15.336

2.  Concise synthesis of the A/BCD-ring fragment of gambieric acid A.

Authors:  Haruhiko Fuwa; Ryo Fukazawa; Makoto Sasaki
Journal:  Front Chem       Date:  2015-01-13       Impact factor: 5.221

3.  Identification of ciguatoxins in a shark involved in a fatal food poisoning in the Indian Ocean.

Authors:  Jorge Diogène; Laia Reverté; Maria Rambla-Alegre; Vanessa Del Río; Pablo de la Iglesia; Mònica Campàs; Oscar Palacios; Cintia Flores; Josep Caixach; Christian Ralijaona; Iony Razanajatovo; Agathe Pirog; Hélène Magalon; Nathalie Arnich; Jean Turquet
Journal:  Sci Rep       Date:  2017-08-15       Impact factor: 4.379

Review 4.  Biotechnological and Pharmacological Applications of Biotoxins and Other Bioactive Molecules from Dinoflagellates.

Authors:  Joana Assunção; A Catarina Guedes; F Xavier Malcata
Journal:  Mar Drugs       Date:  2017-12-20       Impact factor: 5.118

Review 5.  Synthesis-Driven Stereochemical Assignment of Marine Polycyclic Ether Natural Products.

Authors:  Haruhiko Fuwa
Journal:  Mar Drugs       Date:  2021-04-29       Impact factor: 5.118

Review 6.  Alzheimer's Disease and Toxins Produced by Marine Dinoflagellates: An Issue to Explore.

Authors:  Maria João Botelho; Jelena Milinovic; Narcisa M Bandarra; Carlos Vale
Journal:  Mar Drugs       Date:  2022-04-02       Impact factor: 6.085

7.  Total synthesis and complete configurational assignment of amphirionin-2.

Authors:  Shota Kato; Daichi Mizukami; Tomoya Sugai; Masashi Tsuda; Haruhiko Fuwa
Journal:  Chem Sci       Date:  2020-11-20       Impact factor: 9.825

8.  Synthesis of α,α'-trans-oxepanes through an organocatalytic oxa-conjugate addition reaction.

Authors:  Megan L Lanier; Amanda C Kasper; Hyoungsu Kim; Jiyong Hong
Journal:  Org Lett       Date:  2014-04-11       Impact factor: 6.005

Review 9.  Contemporary Strategies for the Synthesis of Tetrahydropyran Derivatives: Application to Total Synthesis of Neopeltolide, a Marine Macrolide Natural Product.

Authors:  Haruhiko Fuwa
Journal:  Mar Drugs       Date:  2016-03-25       Impact factor: 5.118

Review 10.  Ciguatera Mini Review: 21st Century Environmental Challenges and the Interdisciplinary Research Efforts Rising to Meet Them.

Authors:  Christopher R Loeffler; Luciana Tartaglione; Miriam Friedemann; Astrid Spielmeyer; Oliver Kappenstein; Dorina Bodi
Journal:  Int J Environ Res Public Health       Date:  2021-03-15       Impact factor: 3.390
  10 in total

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