Literature DB >> 22779193

[Clinical study on naoxintong capsule for stroke recovery of Qi-deficiency and blood-stasis syndrome].

Liya Su1, Yingkun Li, Bin Lv, Haiwang Ji, Hong Ding, Lingxiang Hu, Suqin Fang, Hui Liang, Xiaoju Cao, Zhong Wang.   

Abstract

OBJECTIVE: To study the efficacy and safety of Naoxintong capsule treatment of stroke recovery with Qi-deficiency and blood-stasis syndrome (cerebral infarction), and to compared the non-inferiority analysis with the positive drug Tongxinluo capsule.
METHOD: Taking Tongxinluo capsules as control, randomized, double-blind, controlled, multi-center clinical experiments were studied. The evaluating indexes included the decrease of integral value of stroke patients, changes in traditional Chinese medicine, the improvement of the patient viability status (disability level), Chinese stroke scale (CSS), activities of daily living (DAL) scale and barthel index (BI ) points. RESULT: The total effect of the two groups, Chinese and other symptoms, showed no significant statistical significance.
CONCLUSION: Naoxintong capsule stroke recovery, with Qi-deficiency and blood-stasis syndrome (cerebral infarction) has a therapeutic effect, and more secure.

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Year:  2011        PMID: 22779193

Source DB:  PubMed          Journal:  Zhongguo Zhong Yao Za Zhi        ISSN: 1001-5302


  9 in total

1.  Comparison of Aspirin and Naoxintong Capsule () with Adjusted-Dose Warfarin in Elderly Patients with High-Risk of Non-Valvular Atrial Fibrillation and Genetic Variants of Vitamin K Epoxide Reductase.

Authors:  Huan Wang; Xiao-Kai Zhou; Li-Fan Zheng; Xiao-Ying Wu; Hui Chen
Journal:  Chin J Integr Med       Date:  2016-02-26       Impact factor: 1.978

2.  Naoxintong attenuates Ischaemia/reperfusion Injury through inhibiting NLRP3 inflammasome activation.

Authors:  Yaqiong Wang; Xiaoxiang Yan; Shouling Mi; Zhang Li; Yuexiang Wang; Hong Zhu; Xiaolei Sun; Buchang Zhao; Chao Zhao; Yunzeng Zou; Kai Hu; Xiaoqiang Ding; Aijun Sun; Junbo Ge
Journal:  J Cell Mol Med       Date:  2016-10-26       Impact factor: 5.310

3.  Naoxintong/PPARγ Signaling Inhibits Cardiac Hypertrophy via Activation of Autophagy.

Authors:  Shuping Yuan; Jianhua Jin; Lu Chen; Yongzhong Hou; Hong Wang
Journal:  Evid Based Complement Alternat Med       Date:  2017-02-15       Impact factor: 2.629

4.  Systems Pharmacology-Based Approach to Comparatively Study the Independent and Synergistic Mechanisms of Danhong Injection and Naoxintong Capsule in Ischemic Stroke Treatment.

Authors:  Junfeng Zhu; Xiaojiao Yi; Yiwen Zhang; Zongfu Pan; Like Zhong; Ping Huang
Journal:  Evid Based Complement Alternat Med       Date:  2019-02-04       Impact factor: 2.629

5.  Yi-Zhi-Fang-Dai Formula Exerts Neuroprotective Effects Against Pyroptosis and Blood-Brain Barrier-Glymphatic Dysfunctions to Prevent Amyloid-Beta Acute Accumulation After Cerebral Ischemia and Reperfusion in Rats.

Authors:  Zhongkuan Lyu; Qiyue Li; Zhonghai Yu; Yuanjin Chan; Lei Fu; Yaming Li; Chunyan Zhang
Journal:  Front Pharmacol       Date:  2021-12-15       Impact factor: 5.810

6.  Identification of "Multiple Components-Multiple Targets-Multiple Pathways" Associated with Naoxintong Capsule in the Treatment of Heart Diseases Using UPLC/Q-TOF-MS and Network Pharmacology.

Authors:  Xianghui Ma; Bin Lv; Pan Li; Xiaoqing Jiang; Qian Zhou; Xiaoying Wang; Xiumei Gao
Journal:  Evid Based Complement Alternat Med       Date:  2016-03-31       Impact factor: 2.629

7.  Naoxintong Protects Primary Neurons from Oxygen-Glucose Deprivation/Reoxygenation Induced Injury through PI3K-Akt Signaling Pathway.

Authors:  Yan Ma; Pei Zhao; Jinqiang Zhu; Chen Yan; Lin Li; Han Zhang; Meng Zhang; Xiumei Gao; Xiang Fan
Journal:  Evid Based Complement Alternat Med       Date:  2016-02-02       Impact factor: 2.629

8.  NaoXinTong Capsules inhibit the development of diabetic nephropathy in db/db mice.

Authors:  Shu Yang; Mengyang Liu; Yuanli Chen; Chuanrui Ma; Lipei Liu; Buchang Zhao; Yong Wang; Xiaoju Li; Yan Zhu; Xiumei Gao; Deling Kong; Yajun Duan; Jihong Han; Xiaoxiao Yang
Journal:  Sci Rep       Date:  2018-06-14       Impact factor: 4.379

9.  Synergic Neuroprotection Between Ligusticum Chuanxiong Hort and Borneol Against Ischemic Stroke by Neurogenesis via Modulating Reactive Astrogliosis and Maintaining the Blood-Brain Barrier.

Authors:  Bin Yu; Yao Yao; Xiaofeng Zhang; Ming Ruan; Zhennian Zhang; Li Xu; Tao Liang; Jinfu Lu
Journal:  Front Pharmacol       Date:  2021-06-16       Impact factor: 5.810

  9 in total

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