Literature DB >> 22778429

Finding a druggable target for schizophrenia.

Beatriz Rico1.   

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Year:  2012        PMID： 22778429      PMCID： PMC3409780          DOI： 10.1073/pnas.1209389109

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  19 in total

1.  Further evidence for association between ErbB4 and schizophrenia and influence on cognitive intermediate phenotypes in healthy controls.

Authors:  K K Nicodemus; A Luna; R Vakkalanka; T Goldberg; M Egan; R E Straub; D R Weinberger
Journal:  Mol Psychiatry       Date:  2006-12       Impact factor: 15.992

2.  Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy.

Authors:  Amanda J Law; Yanhong Wang; Yoshitatsu Sei; Patricio O'Donnell; Patrick Piantadosi; Francesco Papaleo; Richard E Straub; Wenwei Huang; Craig J Thomas; Radhakrishna Vakkalanka; Aaron D Besterman; Barbara K Lipska; Thomas M Hyde; Paul J Harrison; Joel E Kleinman; Daniel R Weinberger
Journal:  Proc Natl Acad Sci U S A       Date:  2012-06-11       Impact factor: 11.205

3.  The involvement of ErbB4 with schizophrenia: association and expression studies.

Authors:  Gilad Silberberg; Ariel Darvasi; Ronit Pinkas-Kramarski; Ruth Navon
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2006-03-05       Impact factor: 3.568

4.  Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease.

Authors:  Amanda J Law; Barbara K Lipska; Cynthia Shannon Weickert; Thomas M Hyde; Richard E Straub; Ryota Hashimoto; Paul J Harrison; Joel E Kleinman; Daniel R Weinberger
Journal:  Proc Natl Acad Sci U S A       Date:  2006-04-17       Impact factor: 11.205

5.  Neuregulin 1 and susceptibility to schizophrenia.

Authors:  Hreinn Stefansson; Engilbert Sigurdsson; Valgerdur Steinthorsdottir; Soley Bjornsdottir; Thordur Sigmundsson; Shyamali Ghosh; Jon Brynjolfsson; Steinunn Gunnarsdottir; Omar Ivarsson; Thomas T Chou; Omar Hjaltason; Birgitta Birgisdottir; Helgi Jonsson; Vala G Gudnadottir; Elsa Gudmundsdottir; Asgeir Bjornsson; Brynjolfur Ingvarsson; Andres Ingason; Sigmundur Sigfusson; Hronn Hardardottir; Richard P Harvey; Donna Lai; Mingdong Zhou; Daniela Brunner; Vincent Mutel; Acuna Gonzalo; Greg Lemke; Jesus Sainz; Gardar Johannesson; Thorkell Andresson; Daniel Gudbjartsson; Andrei Manolescu; Michael L Frigge; Mark E Gurney; Augustine Kong; Jeffrey R Gulcher; Hannes Petursson; Kari Stefansson
Journal:  Am J Hum Genet       Date:  2002-07-23       Impact factor: 11.025

6.  Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia.

Authors:  Tom Walsh; Jon M McClellan; Shane E McCarthy; Anjené M Addington; Sarah B Pierce; Greg M Cooper; Alex S Nord; Mary Kusenda; Dheeraj Malhotra; Abhishek Bhandari; Sunday M Stray; Caitlin F Rippey; Patricia Roccanova; Vlad Makarov; B Lakshmi; Robert L Findling; Linmarie Sikich; Thomas Stromberg; Barry Merriman; Nitin Gogtay; Philip Butler; Kristen Eckstrand; Laila Noory; Peter Gochman; Robert Long; Zugen Chen; Sean Davis; Carl Baker; Evan E Eichler; Paul S Meltzer; Stanley F Nelson; Andrew B Singleton; Ming K Lee; Judith L Rapoport; Mary-Claire King; Jonathan Sebat
Journal:  Science       Date:  2008-03-27       Impact factor: 47.728

Review 7.  Schizophrenia as a disorder of neurodevelopment.

Authors:  David A Lewis; Pat Levitt
Journal:  Annu Rev Neurosci       Date:  2002-03-22       Impact factor: 12.449

8.  Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia.

Authors:  Amanda J Law; Joel E Kleinman; Daniel R Weinberger; Cynthia Shannon Weickert
Journal:  Hum Mol Genet       Date:  2006-12-12       Impact factor: 6.150

9.  PIP3 controls synaptic function by maintaining AMPA receptor clustering at the postsynaptic membrane.

Authors:  Kristin L Arendt; María Royo; Mónica Fernández-Monreal; Shira Knafo; Cortney N Petrok; Jeffrey R Martens; José A Esteban
Journal:  Nat Neurosci       Date:  2009-12-13       Impact factor: 24.884

10.  Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia.

Authors:  Nadine Norton; Valentina Moskvina; Derek W Morris; Nicholas J Bray; Stanley Zammit; Nigel M Williams; Hywel J Williams; Anna C Preece; Sarah Dwyer; Jennifer C Wilkinson; Gillian Spurlock; George Kirov; Paul Buckland; John L Waddington; Michael Gill; Aiden P Corvin; Michael J Owen; Michael C O'Donovan
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2006-01-05       Impact factor: 3.568
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  4 in total

Review 1.  The PI3K signaling pathway as a pharmacological target in Autism related disorders and Schizophrenia.

Authors:  Lilian Enriquez-Barreto; Miguel Morales
Journal:  Mol Cell Ther       Date:  2016-02-11

2.  Evidence that a psychopathology interactome has diagnostic value, predicting clinical needs: an experience sampling study.

Authors:  Jim van Os; Tineke Lataster; Philippe Delespaul; Marieke Wichers; Inez Myin-Germeys
Journal:  PLoS One       Date:  2014-01-23       Impact factor: 3.240

Review 3.  Neuron-specific regulation of class I PI3K catalytic subunits and their dysfunction in brain disorders.

Authors:  Christina Gross; Gary J Bassell
Journal:  Front Mol Neurosci       Date:  2014-02-13       Impact factor: 5.639

4.  Neuregulin signaling pathway in smoking behavior.

Authors:  R Gupta; B Qaiser; L He; T S Hiekkalinna; A B Zheutlin; S Therman; M Ollikainen; S Ripatti; M Perola; V Salomaa; L Milani; T D Cannon; P A F Madden; T Korhonen; J Kaprio; A Loukola
Journal:  Transl Psychiatry       Date:  2017-08-22       Impact factor: 6.222
  4 in total

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