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Literature DB >> 22778288

The serotonin syndrome as a result of mephedrone toxicity.

Abstract

A 22-year-old male presented to an emergency department by ambulance. His clinical picture included tachycardia, diaphoresis, hypertonia, hyper-reflexia and clonus. The patient became hyperthermic and deteriorated over the next hour. The principal substance ingested was mephedrone and appropriate treatment for the serotonin syndrome resulted in a sustained recovery over 15 h.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2010 PMID： 22778288 PMCID： PMC3029518 DOI： 10.1136/bcr.04.2010.2925

Source DB: PubMed Journal: BMJ Case Rep ISSN： 1757-790X

7 in total

1. The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity.

Authors: E J C Dunkley; G K Isbister; D Sibbritt; A H Dawson; I M Whyte
Journal: QJM Date: 2003-09

2. Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography-mass spectrometry.

Authors: Markus R Meyer; Jens Wilhelm; Frank T Peters; Hans H Maurer
Journal: Anal Bioanal Chem Date: 2010-03-25 Impact factor: 4.142

Review 3. The serotonin syndrome.

Authors: Edward W Boyer; Michael Shannon
Journal: N Engl J Med Date: 2005-03-17 Impact factor: 91.245

4. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain.

Authors: Fumiko Nagai; Ryouichi Nonaka; Kanako Satoh Hisashi Kamimura
Journal: Eur J Pharmacol Date: 2006-12-12 Impact factor: 4.432

5. Recreational use of mephedrone (4-methylmethcathinone, 4-MMC) with associated sympathomimetic toxicity.

Authors: David M Wood; Susannah Davies; Malgorzata Puchnarewicz; Jenny Button; Roland Archer; Hanna Ovaska; John Ramsey; Terry Lee; David W Holt; Paul I Dargan
Journal: J Med Toxicol Date: 2010-09

6. [Mephedrone--Internet drug which seems to have come and stay. Fatal cases in Sweden have drawn attention to previously unknown substance].

Authors: David Gustavsson; Cecilia Escher
Journal: Lakartidningen Date: 2009 Oct 21-27

7. Multiple-drug toxicity caused by the coadministration of 4-methylmethcathinone (mephedrone) and heroin.

Authors: Amber J Dickson; Shawn P Vorce; Barry Levine; Marilyn R Past
Journal: J Anal Toxicol Date: 2010-04 Impact factor: 3.367

7 in total

5 in total

Review 1. The preclinical pharmacology of mephedrone; not just MDMA by another name.

Authors: A R Green; M V King; S E Shortall; K C F Fone
Journal: Br J Pharmacol Date: 2014-05 Impact factor: 8.739

2. Pharmacotherapy of Patients Taking New Psychoactive Substances: A Systematic Review and Analysis of Case Reports.

Authors: Michal Ordak; Aleksandra Zmysłowska; Miłosz Bielski; Daniel Rybak; Maja Tomaszewska; Katarzyna Wyszomierska; Aleksandra Kmiec; Natalia Garlicka; Maria Zalewska; Michal Zalewski; Tadeusz Nasierowski; Elzbieta Muszynska; Magdalena Bujalska-Zadrozny
Journal: Front Psychiatry Date: 2021-04-23 Impact factor: 4.157