Literature DB >> 22778189

Gastric ulcers and swollen kidneys: a rare diagnosis complicating Crohn's disease.

C Ormerod1, S Sarkar, B Woodcock, D White, S Lal.   

Abstract

We present a case of a 48-year-old woman with Crohn's colitis admitted with abdominal pain and fever. She had been started on azathioprine 6 months before presentation and had received three doses of infliximab. Abdominal CT scan revealed a liver abscess. Azathioprine was stopped and antibiotics started. She was subsequently discharged with follow-up imaging planned. She presented 3 weeks later with haematemesis. Gastroscopy revealed multiple gastric ulcers. A repeat CT scan showed bilateral renal masses and a renal biopsy was arranged. Gastric and renal biopsies were consistent with B cell lymphoma. Chemotherapy was started and resulted in improvement in CT scan findings as well as ulcer healing.

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Year:  2010        PMID: 22778189      PMCID: PMC3029454          DOI: 10.1136/bcr.03.2010.2809

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  5 in total

1.  Hepatosplenic T cell lymphoma in inflammatory bowel disease.

Authors:  Matthew Shale; Ed Kanfer; Remo Panaccione; Subrata Ghosh
Journal:  Gut       Date:  2008-07-30       Impact factor: 23.059

2.  Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine.

Authors:  A Kandiel; A G Fraser; B I Korelitz; C Brensinger; J D Lewis
Journal:  Gut       Date:  2005-08       Impact factor: 23.059

3.  Introduction of combined CHOP plus rituximab therapy dramatically improved outcome of diffuse large B-cell lymphoma in British Columbia.

Authors:  Laurie H Sehn; Jane Donaldson; Mukesh Chhanabhai; Catherine Fitzgerald; Karamjit Gill; Richard Klasa; Nicol MacPherson; Susan O'Reilly; John J Spinelli; Judy Sutherland; Kenneth S Wilson; Randy D Gascoyne; Joseph M Connors
Journal:  J Clin Oncol       Date:  2005-06-13       Impact factor: 44.544

4.  Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study.

Authors:  Laurent Beaugerie; Nicole Brousse; Anne Marie Bouvier; Jean Frédéric Colombel; Marc Lémann; Jacques Cosnes; Xavier Hébuterne; Antoine Cortot; Yoram Bouhnik; Jean Pierre Gendre; Tabassome Simon; Marc Maynadié; Olivier Hermine; Jean Faivre; Fabrice Carrat
Journal:  Lancet       Date:  2009-11-07       Impact factor: 79.321

Review 5.  Lymphoma risk in inflammatory bowel disease: is it the disease or its treatment?

Authors:  Jennifer L Jones; Edward V Loftus
Journal:  Inflamm Bowel Dis       Date:  2007-10       Impact factor: 5.325

  5 in total

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