Literature DB >> 22777707

Small molecule-gold nanorod conjugates selectively target and induce macrophage cytotoxicity towards breast cancer cells.

Erik C Dreaden1, Sandra C Mwakwari, Lauren A Austin, Matthew J Kieffer, Adegboyega K Oyelere, Mostafa A El-Sayed.   

Abstract

Gold nanoparticles are known to activate anti-tumor potential in macrophage immune cells; however, the subsequent effects of these cells on others nearby are poorly understood. A novel gold-nanoparticle conjugate that selectively targets and induces cytotoxic activity of tumor-associated macrophages towards breast cancer cells in co-culture is synthesized. These constructs are promising new tools for studying fundamental biological interactions with nanoscale materials and candidates for emerging macrophage-mediated delivery applications.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID： 22777707      PMCID： PMC3459581          DOI： 10.1002/smll.201200333

Source DB:  PubMed          Journal:  Small        ISSN： 1613-6810            Impact factor:   13.281


  38 in total

1.  Evidence for in vivo macrophage mediated tumor uptake of paramagnetic/fluorescent liposomes.

Authors:  Daniela Delli Castelli; Enzo Terreno; Claudia Cabella; Linda Chaabane; Stefania Lanzardo; Lorenzo Tei; Massimo Visigalli; Silvio Aime
Journal:  NMR Biomed       Date:  2009-12       Impact factor: 4.044

2.  Preclinical evaluation of Raman nanoparticle biodistribution for their potential use in clinical endoscopy imaging.

Authors:  Cristina L Zavaleta; Keith B Hartman; Zheng Miao; Michelle L James; Paul Kempen; Avnesh S Thakor; Carsten H Nielsen; Robert Sinclair; Zhen Cheng; Sanjiv S Gambhir
Journal:  Small       Date:  2011-05-24       Impact factor: 13.281

3.  Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice.

Authors:  Marija Djukic; Alexander Mildner; Hauke Schmidt; Dirk Czesnik; Wolfgang Brück; Josef Priller; Roland Nau; Marco Prinz
Journal:  Brain       Date:  2006-08-03       Impact factor: 13.501

4.  Gold nanocages as photothermal transducers for cancer treatment.

Authors:  Jingyi Chen; Charles Glaus; Richard Laforest; Qiang Zhang; Miaoxian Yang; Michael Gidding; Michael J Welch; Younan Xia
Journal:  Small       Date:  2010-04-09       Impact factor: 13.281

5.  Deep penetration of a PDT drug into tumors by noncovalent drug-gold nanoparticle conjugates.

Authors:  Yu Cheng; Joseph D Meyers; Ann-Marie Broome; Malcolm E Kenney; James P Basilion; Clemens Burda
Journal:  J Am Chem Soc       Date:  2011-02-04       Impact factor: 15.419

6.  Quantum dots are phagocytized by macrophages and colocalize with experimental gliomas.

Authors:  Heather Jackson; Osman Muhammad; Hamid Daneshvar; Jennifer Nelms; Alexandra Popescu; Michael A Vogelbaum; Marcel Bruchez; Steven A Toms
Journal:  Neurosurgery       Date:  2007-03       Impact factor: 4.654

7.  Cytotoxicity and immunological response of gold and silver nanoparticles of different sizes.

Authors:  Hung-Jen Yen; Shan-Hui Hsu; Ching-Lin Tsai
Journal:  Small       Date:  2009-07       Impact factor: 13.281

8.  Detection and differentiation of normal, cancerous, and metastatic cells using nanoparticle-polymer sensor arrays.

Authors:  Avinash Bajaj; Oscar R Miranda; Ik-Bum Kim; Ronnie L Phillips; D Joseph Jerry; Uwe H F Bunz; Vincent M Rotello
Journal:  Proc Natl Acad Sci U S A       Date:  2009-06-23       Impact factor: 11.205

9.  Modulating pharmacokinetics, tumor uptake and biodistribution by engineered nanoparticles.

Authors:  Rochelle R Arvizo; Oscar R Miranda; Daniel F Moyano; Chad A Walden; Karuna Giri; Resham Bhattacharya; J David Robertson; Vincent M Rotello; Joel M Reid; Priyabrata Mukherjee
Journal:  PLoS One       Date:  2011-09-13       Impact factor: 3.240

10.  Tumor-associated macrophages are predominant carriers of cyclodextrin-based nanoparticles into gliomas.

Authors:  Darya Alizadeh; Leying Zhang; Jungyeon Hwang; Thomas Schluep; Behnam Badie
Journal:  Nanomedicine       Date:  2009-11-05       Impact factor: 5.307
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  21 in total

1.  Preparation and Photoacoustic Analysis of Cellular Vehicles Containing Gold Nanorods.

Authors:  Lucia Cavigli; Francesca Tatini; Claudia Borri; Fulvio Ratto; Sonia Centi; Alberto Cini; Beatrice Lelli; Paolo Matteini; Roberto Pini
Journal:  J Vis Exp       Date:  2016-05-02       Impact factor: 1.355

Review 2.  Nanoscale materials for hyperthermal theranostics.

Authors:  Bennett E Smith; Paden B Roder; Xuezhe Zhou; Peter J Pauzauskie
Journal:  Nanoscale       Date:  2015-04-28       Impact factor: 7.790

3.  Uniform brain tumor distribution and tumor associated macrophage targeting of systemically administered dendrimers.

Authors:  Fan Zhang; Panagiotis Mastorakos; Manoj K Mishra; Antonella Mangraviti; Lee Hwang; Jinyuan Zhou; Justin Hanes; Henry Brem; Alessandro Olivi; Betty Tyler; Rangaramanujam M Kannan
Journal:  Biomaterials       Date:  2015-03-18       Impact factor: 12.479

4.  P-glycoprotein-dependent trafficking of nanoparticle-drug conjugates.

Authors:  Erik C Dreaden; Idris O Raji; Lauren A Austin; Shaghayegh Fathi; Sandra C Mwakwari; William H Humphries; Bin Kang; Adegboyega K Oyelere; Mostafa A El-Sayed
Journal:  Small       Date:  2014-02-25       Impact factor: 13.281

5.  Targeting of tumor-associated macrophages made possible by PEG-sheddable, mannose-modified nanoparticles.

Authors:  Saijie Zhu; Mengmeng Niu; Hannah O'Mary; Zhengrong Cui
Journal:  Mol Pharm       Date:  2013-08-06       Impact factor: 4.939

6.  Vascular targeting to the SST2 receptor improves the therapeutic response to near-IR two-photon activated PDT for deep-tissue cancer treatment.

Authors:  Jean R Starkey; Elizabeth M Pascucci; Mikhail A Drobizhev; Aleisha Elliott; Aleksander K Rebane
Journal:  Biochim Biophys Acta       Date:  2013-06-07

Review 7.  Cellular uptake of nanoparticles: journey inside the cell.

Authors:  Shahed Behzadi; Vahid Serpooshan; Wei Tao; Majd A Hamaly; Mahmoud Y Alkawareek; Erik C Dreaden; Dennis Brown; Alaaldin M Alkilany; Omid C Farokhzad; Morteza Mahmoudi
Journal:  Chem Soc Rev       Date:  2017-07-17       Impact factor: 54.564

8.  Two-wave nanotherapy to target the stroma and optimize gemcitabine delivery to a human pancreatic cancer model in mice.

Authors:  Huan Meng; Yang Zhao; Juyao Dong; Min Xue; Yu-Shen Lin; Zhaoxia Ji; Wilson X Mai; Haiyuan Zhang; Chong Hyun Chang; C Jeffrey Brinker; Jeffrey I Zink; Andre E Nel
Journal:  ACS Nano       Date:  2013-10-28       Impact factor: 15.881

9.  Photosensitizer-gold nanorod composite for targeted multimodal therapy.

Authors:  Jian Wang; Mingxu You; Guizhi Zhu; Mohammed Ibrahim Shukoor; Zhuo Chen; Zilong Zhao; Meghan B Altman; Quan Yuan; Zhi Zhu; Yan Chen; Cheng Zhi Huang; Weihong Tan
Journal:  Small       Date:  2013-05-10       Impact factor: 13.281

Review 10.  Macrophages associated with tumors as potential targets and therapeutic intermediates.

Authors:  Serguei Vinogradov; Galya Warren; Xin Wei
Journal:  Nanomedicine (Lond)       Date:  2014-04       Impact factor: 5.307
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