Literature DB >> 22776331

Gene-environment interactions in Parkinson's disease: specific evidence in humans and mammalian models.

Jason R Cannon1, J Timothy Greenamyre.   

Abstract

Interactions between genetic factors and environmental exposures are thought to be major contributors to the etiology of Parkinson's disease. While such interactions are poorly defined and incompletely understood, recent epidemiological studies have identified specific interactions of potential importance to human PD. In this review, the most current data on gene-environment interactions in PD from human studies are critically discussed. Animal models have also highlighted the importance of genetic susceptibility to toxicant exposure and data of potential relevance to human PD are discussed. Goals and needs for the future of the field are proposed. 2012 Elsevier Inc. All rights reserved

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Year:  2012        PMID： 22776331      PMCID： PMC3815566          DOI： 10.1016/j.nbd.2012.06.025

Source DB:  PubMed          Journal:  Neurobiol Dis        ISSN： 0969-9961            Impact factor:   5.996


  130 in total

1.  Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease.

Authors:  Fang Liu; Jamie L Nguyen; John D Hulleman; Li Li; Jean-Christophe Rochet
Journal:  J Neurochem       Date:  2008-06-01       Impact factor: 5.372

Review 2.  The paradoxical cell biology of alpha-Synucle.

Authors:  Subhojit Roy
Journal:  Results Probl Cell Differ       Date:  2009

3.  Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).

Authors:  Eva Andres-Mateos; Rebeca Mejias; Masayuki Sasaki; Xiaojie Li; Brian M Lin; Saskia Biskup; Li Zhang; Rebecca Banerjee; Bobby Thomas; Lichuan Yang; Guosheng Liu; M Flint Beal; David L Huso; Ted M Dawson; Valina L Dawson
Journal:  J Neurosci       Date:  2009-12-16       Impact factor: 6.167

4.  Dopamine transporter genetic variants and pesticides in Parkinson's disease.

Authors:  Beate R Ritz; Angelika D Manthripragada; Sadie Costello; Sarah J Lincoln; Matthew J Farrer; Myles Cockburn; Jeff Bronstein
Journal:  Environ Health Perspect       Date:  2009-02-22       Impact factor: 9.031

5.  A highly reproducible rotenone model of Parkinson's disease.

Authors:  Jason R Cannon; Victor Tapias; Hye Mee Na; Anthony S Honick; Robert E Drolet; J Timothy Greenamyre
Journal:  Neurobiol Dis       Date:  2009-05       Impact factor: 5.996

6.  Trichloroethylene induces dopaminergic neurodegeneration in Fisher 344 rats.

Authors:  Mei Liu; Dong-Young Choi; Randy L Hunter; Jignesh D Pandya; Wayne A Cass; Patrick G Sullivan; Hyoung-Chun Kim; Don M Gash; Guoying Bing
Journal:  J Neurochem       Date:  2009-11-17       Impact factor: 5.372

7.  DJ-1 knock-down in astrocytes impairs astrocyte-mediated neuroprotection against rotenone.

Authors:  Steven J Mullett; David A Hinkle
Journal:  Neurobiol Dis       Date:  2008-09-30       Impact factor: 5.996

Review 8.  Multiple roles for nicotine in Parkinson's disease.

Authors:  Maryka Quik; Luping Z Huang; Neeraja Parameswaran; Tanuja Bordia; Carla Campos; Xiomara A Perez
Journal:  Biochem Pharmacol       Date:  2009-05-09       Impact factor: 5.858

9.  Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology.

Authors:  A Grünewald; M E Gegg; J-W Taanman; R H King; N Kock; C Klein; A H V Schapira
Journal:  Exp Neurol       Date:  2009-06-03       Impact factor: 5.330

10.  Well-water consumption and Parkinson's disease in rural California.

Authors:  Nicole M Gatto; Myles Cockburn; Jeff Bronstein; Angelika D Manthripragada; Beate Ritz
Journal:  Environ Health Perspect       Date:  2009-07-31       Impact factor: 9.031
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  64 in total

1.  Superoxide Dismutases SOD1 and SOD2 Rescue the Toxic Effect of Dopamine-Derived Products in Human SH-SY5Y Neuroblastoma Cells.

Authors:  Alice Biosa; Federica De Lazzari; Anna Masato; Roberta Filograna; Nicoletta Plotegher; Mariano Beltramini; Luigi Bubacco; Marco Bisaglia
Journal:  Neurotox Res       Date:  2019-06-21       Impact factor: 3.911

2.  Why our patients (and we) need basic science research.

Authors:  Nina F Schor
Journal:  Neurology       Date:  2013-05-28       Impact factor: 9.910

3.  Characterizing dysbiosis of gut microbiome in PD: evidence for overabundance of opportunistic pathogens.

Authors:  Zachary D Wallen; Mary Appah; Marissa N Dean; Cheryl L Sesler; Stewart A Factor; Eric Molho; Cyrus P Zabetian; David G Standaert; Haydeh Payami
Journal:  NPJ Parkinsons Dis       Date:  2020-06-12

4.  Mitochondrial DNA damage: molecular marker of vulnerable nigral neurons in Parkinson's disease.

Authors:  Laurie H Sanders; Jennifer McCoy; Xiaoping Hu; Pier G Mastroberardino; Bryan C Dickinson; Christopher J Chang; Charleen T Chu; Bennett Van Houten; J T Greenamyre
Journal:  Neurobiol Dis       Date:  2014-06-27       Impact factor: 5.996

5.  Mitochondrially targeted cytochrome P450 2D6 is involved in monomethylamine-induced neuronal damage in mouse models.

Authors:  Mrittika Chattopadhyay; Anindya Roy Chowdhury; Ting Feng; Charles-Antoine Assenmacher; Enrico Radaelli; F Peter Guengerich; Narayan G Avadhani
Journal:  J Biol Chem       Date:  2019-05-20       Impact factor: 5.157

Review 6.  Oxidative damage to macromolecules in human Parkinson disease and the rotenone model.

Authors:  Laurie H Sanders; J Timothy Greenamyre
Journal:  Free Radic Biol Med       Date:  2013-01-15       Impact factor: 7.376

7.  Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways.

Authors:  Annadurai Anandhan; Humberto Rodriguez-Rocha; Iryna Bohovych; Amy M Griggs; Laura Zavala-Flores; Elsa M Reyes-Reyes; Javier Seravalli; Lia A Stanciu; Jaekwon Lee; Jean-Christophe Rochet; Oleh Khalimonchuk; Rodrigo Franco
Journal:  Neurobiol Dis       Date:  2014-12-08       Impact factor: 5.996

8.  Fungal-derived semiochemical 1-octen-3-ol disrupts dopamine packaging and causes neurodegeneration.

Authors:  Arati A Inamdar; Muhammad M Hossain; Alison I Bernstein; Gary W Miller; Jason R Richardson; Joan Wennstrom Bennett
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-11       Impact factor: 11.205

9.  Editor's Highlight: Nlrp3 Is Required for Inflammatory Changes and Nigral Cell Loss Resulting From Chronic Intragastric Rotenone Exposure in Mice.

Authors:  Eileen M Martinez; Alison L Young; Yash R Patankar; Brent L Berwin; Li Wang; Katharine M von Herrmann; Jaclyn M Weier; Matthew C Havrda
Journal:  Toxicol Sci       Date:  2017-09-01       Impact factor: 4.849

10.  G2019S LRRK2 and aging confer susceptibility to proteasome inhibitor-induced neurotoxicity in nigrostriatal dopaminergic system.

Authors:  Qian Xiao; Suosuo Yang; Weidong Le
Journal:  J Neural Transm (Vienna)       Date:  2015-08-08       Impact factor: 3.575
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