Literature DB >> 22772540

Execution of sepsis trials needs an overhaul, experts say.

Roxanne Khamsi.   

Abstract

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Year:  2012        PMID： 22772540     DOI： 10.1038/nm0712-998b

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  3 in total

1.  The search for effective therapy for sepsis: back to the drawing board?

Authors:  Derek C Angus
Journal:  JAMA       Date:  2011-12-21       Impact factor: 56.272

2.  Intensive versus conventional glucose control in critically ill patients.

Authors:  Simon Finfer; Dean R Chittock; Steve Yu-Shuo Su; Deborah Blair; Denise Foster; Vinay Dhingra; Rinaldo Bellomo; Deborah Cook; Peter Dodek; William R Henderson; Paul C Hébert; Stephane Heritier; Daren K Heyland; Colin McArthur; Ellen McDonald; Imogen Mitchell; John A Myburgh; Robyn Norton; Julie Potter; Bruce G Robinson; Juan J Ronco
Journal:  N Engl J Med       Date:  2009-03-24       Impact factor: 91.245

3.  IL17A genetic variation is associated with altered susceptibility to Gram-positive infection and mortality of severe sepsis.

Authors:  Taka-aki Nakada; James A Russell; John H Boyd; Keith R Walley
Journal:  Crit Care       Date:  2011-10-25       Impact factor: 9.097
  3 in total
  6 in total

1.  Of men, not mice.

Authors: 
Journal:  Nat Med       Date:  2013-04       Impact factor: 53.440

2.  Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice.

Authors:  Markus Huber-Lang; Andreas Barratt-Due; Søren E Pischke; Øystein Sandanger; Per H Nilsson; Miles A Nunn; Stephanie Denk; Wilhelm Gaus; Terje Espevik; Tom E Mollnes
Journal:  J Immunol       Date:  2014-04-30       Impact factor: 5.422

3.  P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy.

Authors:  Huan Wang; Ling-Juan Hong; Ji-Yun Huang; Quan Jiang; Rong-Rong Tao; Chao Tan; Nan-Nan Lu; Cheng-Kun Wang; Muhammad M Ahmed; Ying-Mei Lu; Zhi-Rong Liu; Wei-Xing Shi; En-Yin Lai; Christopher S Wilcox; Feng Han
Journal:  Cell Res       Date:  2015-05-22       Impact factor: 25.617

4.  Chronic kidney disease is associated with a higher 90-day mortality than other chronic medical conditions in patients with sepsis.

Authors:  Ashham Mansur; Evelyn Mulwande; Maximilian Steinau; Ingo Bergmann; Aron Frederik Popov; Michael Ghadimi; Tim Beissbarth; Martin Bauer; José Hinz
Journal:  Sci Rep       Date:  2015-05-21       Impact factor: 4.379

5.  Primary bacteraemia is associated with a higher mortality risk compared with pulmonary and intra-abdominal infections in patients with sepsis: a prospective observational cohort study.

Authors:  Ashham Mansur; Yvonne Klee; Aron Frederik Popov; Joachim Erlenwein; Michael Ghadimi; Tim Beissbarth; Martin Bauer; José Hinz
Journal:  BMJ Open       Date:  2015-01-06       Impact factor: 2.692

6.  Quantification of microcirculatory blood flow: a sensitive and clinically relevant prognostic marker in murine models of sepsis.

Authors:  Claire A Sand; Anna Starr; Catherine D E Wilder; Olena Rudyk; Domenico Spina; Christoph Thiemermann; David F Treacher; Manasi Nandi
Journal:  J Appl Physiol (1985)       Date:  2014-12-04
  6 in total

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