Literature DB >> 227718

Leydig cell function in streptozotocin-induced diabetic rats.

G Paz, Z T Homonnai.   

Abstract

Streptozotocin diabetic rats were infertile as a result of decreased Leydig cell function of the testes. The major changes found were: decreased number of Leydig cells and their spontaneous secretion of testosterone. No change in the receptors to LH on the Leydig cells was observed. LH was found to be obligatory for the regulation of Leydig cell function and fertility.

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Year:  1979        PMID： 227718     DOI： 10.1007/bf01964042

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  DISORDERS OF SEXUAL FUNCTION IN MALE DIABETICS.

Authors:  K SCHOEFFLING; K FEDERLIN; H DITSCHUNEIT; E F PFEIFFER
Journal:  Diabetes       Date:  1963 Nov-Dec       Impact factor: 9.461

2.  The effects of alloxan diabetes on the reproductive system of young male rats.

Authors:  E L HUNT; D W BAILEY
Journal:  Acta Endocrinol (Copenh)       Date:  1961-11

3.  Semen quality and certain disturbances of reproduction in diabetic men.

Authors:  D KLEBANOW; J MACLEOD
Journal:  Fertil Steril       Date:  1960 May-Jun       Impact factor: 7.329

4.  Ovarian binding of intact and desialytated hcg in vivo and in vitro.

Authors:  T Tsuruhara; E V Van Hall; M L Dufau; K J Catt
Journal:  Endocrinology       Date:  1972-08       Impact factor: 4.736

5.  Sexual disturbances in the male diabetic rat.

Authors:  V G Foglia; J M Rosner; B E Lema
Journal:  Horm Metab Res       Date:  1969-03       Impact factor: 2.936

6.  Fertility of the streptozotocin-diabetic male rat.

Authors:  G P Frenkel; Z T Homonnai; N Drasnin; A Sofer; R Kaplan; P F Kraicer
Journal:  Andrologia       Date:  1978 Mar-Apr       Impact factor: 2.775

7.  Gonadotropin binding and stimulation of cyclic adenosine 3':5'-monophosphate and testosterone production in isolated Leydig cells.

Authors:  C Mendelson; M Dufau; K Catt
Journal:  J Biol Chem       Date:  1975-11-25       Impact factor: 5.157

8.  Studies in human reproduction. II. The influence of diabetes mellitus in men upon reproduction.

Authors:  A RUBIN
Journal:  Am J Obstet Gynecol       Date:  1958-07       Impact factor: 8.661

9.  Improvement in the fertility of streptozotocin-diabetic male rats following treatment with insulin and human chrionic gonadotropin.

Authors:  G Paz; Z T Homonnai; A Harell; P F Kraicer
Journal:  Isr J Med Sci       Date:  1978-10

10.  Testicular lesions of streptozotocin diabetic rats.

Authors:  A Oksanen
Journal:  Horm Res       Date:  1975
  10 in total
  7 in total

1.  Effect of streptozotocin diabetes on adenosine-5'-triphosphate, oxygen consumption and steroidogenesis in testis mitochondria from rats.

Authors:  A Benitez; J Pérez Díaz
Journal:  Experientia       Date:  1982-08-15

2.  Antioxidant treatment with edaravone or taurine ameliorates diabetes-induced testicular dysfunction in the rat.

Authors:  Panagiota Tsounapi; Motoaki Saito; Fotios Dimitriadis; Sotirios Koukos; Shogo Shimizu; Keisuke Satoh; Atsushi Takenaka; Nikolaos Sofikitis
Journal:  Mol Cell Biochem       Date:  2012-07-05       Impact factor: 3.396

3.  Effects of hydro-alcoholic extract of Launaea acanthodes on serum gonadotropin and testosterone levels and the structure of seminiferous tubules in hyperglycemic rats.

Authors:  Ameneh Mohammadi; Morteza Behnam-Rassouli; Zeinab Momeni; Naser Mahdavi-Shahri
Journal:  Chin J Integr Med       Date:  2015-12-17       Impact factor: 1.978

4.  Morphological changes in the hypothalamic-hypophyseal-gonadal axis of male rats after twelve months of streptozotocin-induced diabetes.

Authors:  G L Rossi; G Bestetti
Journal:  Diabetologia       Date:  1981-11       Impact factor: 10.122

5.  Evaluation of chromosomal instability in diabetic rats treated with naringin.

Authors:  Saleh A Bakheet; Sabry M Attia
Journal:  Oxid Med Cell Longev       Date:  2011-09-20       Impact factor: 6.543

6.  Contemporaneous effects of diabetes mellitus and hypothyroidism on spermatogenesis and immunolocalization of Claudin-11 inside the seminiferous tubules of mice.

Authors:  Nazar Ali Korejo; Quanwei Wei; Kaizhi Zheng; Dagan Mao; Rashid Ali Korejo; Atta Hussain Shah; Fangxiong Shi
Journal:  BMC Dev Biol       Date:  2018-06-26       Impact factor: 1.978

7.  Animal Models of Diabetes-Related Male Hypogonadism.

Authors:  Anastasia Dimakopoulou; Channa N Jayasena; Utsav K Radia; Metab Algefari; Suks Minhas; Nick Oliver; Waljit S Dhillo
Journal:  Front Endocrinol (Lausanne)       Date:  2019-09-18       Impact factor: 5.555
  7 in total

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