Literature DB >> 22771514

Clinical management of older people with non-small cell lung cancer in England.

Paul Beckett1, Matthew Callister, Laila J Tata, Richard Harrison, Michael D Peake, Roz Stanley, Ian Woolhouse, Mark Slade, Richard B Hubbard.   

Abstract

Data for 25261 patients with non-small cell lung cancer whose details were submitted to the National Lung Cancer Audit in England were analysed to assess the effect of age at diagnosis on their clinical management, after accounting for sex, stage, performance status and comorbidity. Multivariate logistic regression showed the odds of having histocytological confirmation and anticancer treatment decreased progressively with age, and was also lower in women. It is likely that these results have a multifactorial explanation, and further research into the attitudes of patients, carers and healthcare professionals, and clinical trials of treatment in older populations, are necessary.

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Year:  2012        PMID: 22771514     DOI: 10.1136/thoraxjnl-2011-200994

Source DB:  PubMed          Journal:  Thorax        ISSN: 0040-6376            Impact factor:   9.139


  5 in total

1.  Expert consensus panel guidelines on geriatric assessment in oncology.

Authors:  A O'Donovan; S G Mohile; M Leech
Journal:  Eur J Cancer Care (Engl)       Date:  2015-03-11       Impact factor: 2.520

2.  Analysis of the characteristics and prognosis of advanced non-small-cell lung cancer in older patients.

Authors:  Ying Gao; Fei Gao; Jin-Lu Ma; Xiao-Zhi Zhang; Yi Li; Li-Ping Song; Dong-Li Zhao
Journal:  Patient Prefer Adherence       Date:  2015-08-19       Impact factor: 2.711

3.  Accuracy and consequences of same-day, invasive lung cancer workup - a retrospective study in patients treated with surgical resection.

Authors:  Kirsten Riis Madsen; Asbjørn Høegholm; Uffe Bodtger
Journal:  Eur Clin Respir J       Date:  2016-11-30

4.  Efficacy and Prognosis of First-Line EGFR-Tyrosine Kinase Inhibitor Treatment in Older Adults Including Poor Performance Status Patients with EGFR-Mutated Non-Small-Cell Lung Cancer.

Authors:  Cheng-Yu Chang; Chung-Yu Chen; Shih-Chieh Chang; Yi-Chun Lai; Yu-Feng Wei
Journal:  Cancer Manag Res       Date:  2021-09-15       Impact factor: 3.989

5.  Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients.

Authors:  Laura Boldrini; Mirella Giordano; Marco Lucchi; Franca Melfi; Gabriella Fontanini
Journal:  Biomed Rep       Date:  2018-07-02
  5 in total

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