Literature DB >> 22771412

Germ cell tumour of the trachea.

Steven Gamalski1, Javier Munoz, Alicia Diaz-Kuan, Ira Wollner.   

Abstract

A 28-year-old man presented with stridor and dyspnoea. Imaging showed a tracheal mass with severe narrowing of the subglottic airway. Histopathology was consistent with non-seminomatous germ cell tumour. The patient underwent cricotracheal resection and reconstruction of the trachea with tracheostomy. Subsequent positron emission tomography demonstrated new right upper lobe nodules. Postoperative chemotherapy was initiated using the VIP regimen (etoposide, ifosfamide and cisplatin). After four cycles of chemotherapy, CT of the thorax showed interval resolution of most of the pulmonary nodules. Thoracoscopy with right upper and lower lobe wedge resections was performed to remove the residual disease. The patient is currently disease-free and undergoing continued surveillance to assess for clinical, biochemical or radiographical evidence of disease recurrence.

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Mesh:

Year:  2012        PMID: 22771412      PMCID: PMC4542745          DOI: 10.1136/bcr-03-2012-5991

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

1.  Primary mediastinal nonseminomatous germ cell tumors: results of modern therapy including cisplatin-based chemotherapy.

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Journal:  J Clin Oncol       Date:  1998-02       Impact factor: 44.544

Review 2.  Genetics and biology of adult human male germ cell tumors.

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Journal:  Cancer Res       Date:  2000-03-15       Impact factor: 12.701

3.  Cisplatin, etoposide and either bleomycin or ifosfamide in the treatment of disseminated germ cell tumors: final analysis of an intergroup trial.

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Journal:  Cancer       Date:  2003-04-15       Impact factor: 6.860

4.  Intradural lumbar mature teratoma with neuronal and glial tissue component in an adult. Case report.

Authors:  Weiting Gu; Hanbing Shang; Xiaolong Jin; Jing Xie; Weiguo Zhao
Journal:  Neurol Med Chir (Tokyo)       Date:  2010       Impact factor: 1.742

5.  Extragonadal germ cell tumors of the mediastinum and retroperitoneum: results from an international analysis.

Authors:  Carsten Bokemeyer; Craig R Nichols; Jean-P Droz; Hans-J Schmoll; Alan Horwich; Arthur Gerl; Sophie D Fossa; Jörg Beyer; Jörg Pont; Lothar Kanz; Lawrence Einhorn; Jörg T Hartmann
Journal:  J Clin Oncol       Date:  2002-04-01       Impact factor: 44.544

6.  Origin of adult male mediastinal germ-cell tumours.

Authors:  R S Chaganti; E Rodriguez; S Mathew
Journal:  Lancet       Date:  1994-05-07       Impact factor: 79.321

7.  Primary immature mediastinal teratoma in adulthood.

Authors:  K Arai; S Ohta; M Suzuki; H Suzuki
Journal:  Eur J Surg Oncol       Date:  1997-02       Impact factor: 4.424

8.  Clinical relevance of the i(12p) marker chromosome in germ cell tumors.

Authors:  G J Bosl; D H Ilson; E Rodriguez; R J Motzer; V E Reuter; R S Chaganti
Journal:  J Natl Cancer Inst       Date:  1994-03-02       Impact factor: 13.506

Review 9.  European consensus on diagnosis and treatment of germ cell cancer: a report of the European Germ Cell Cancer Consensus Group (EGCCCG).

Authors:  H J Schmoll; R Souchon; S Krege; P Albers; J Beyer; C Kollmannsberger; S D Fossa; N E Skakkebaek; R de Wit; K Fizazi; J P Droz; G Pizzocaro; G Daugaard; P H M de Mulder; A Horwich; T Oliver; R Huddart; G Rosti; L Paz Ares; O Pont; J T Hartmann; N Aass; F Algaba; M Bamberg; I Bodrogi; C Bokemeyer; J Classen; S Clemm; S Culine; M de Wit; H G Derigs; K P Dieckmann; M Flasshove; X Garcia del Muro; A Gerl; J R Germa-Lluch; M Hartmann; A Heidenreich; W Hoeltl; J Joffe; W Jones; G Kaiser; O Klepp; S Kliesch; L Kisbenedek; K U Koehrmann; M Kuczyk; M P Laguna; O Leiva; V Loy; M D Mason; G M Mead; R P Mueller; N Nicolai; G O N Oosterhof; T Pottek; O Rick; H Schmidberger; F Sedlmayer; W Siegert; U Studer; S Tjulandin; H von der Maase; P Walz; S Weinknecht; L Weissbach; E Winter; C Wittekind
Journal:  Ann Oncol       Date:  2004-09       Impact factor: 32.976

  9 in total

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