Sang-Hwa Lee1, Hyun-Joong Yoon. 1. Associate Professor, Department of Oral and Maxillofacial Surgery, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
Abstract
OBJECTIVE: This study was undertaken to describe 2 cases of localized Langerhans cell histiocytosis (LLCH) of the mandible that healed quickly following intralesional infiltration of corticosteroids. STUDY DESIGN: Two patients with LLCH of the mandible were treated in a 1-stage procedure with intralesional injection of methylprednisolone. Symptoms of pain were quickly relieved and the swelling receded. Periodic orthopantomogram and computerized tomography after corticosteroid injection revealed continuous regression of mandibular osteolysis and a favorable osseous consolidation in the lesions. CONCLUSIONS: The results of this report suggest that intralesional injection of corticosteroids should be the initial choice of treatment of LLCH of the mandible, especially in children to preserve tooth germs.
OBJECTIVE: This study was undertaken to describe 2 cases of localized Langerhans cell histiocytosis (LLCH) of the mandible that healed quickly following intralesional infiltration of corticosteroids. STUDY DESIGN: Two patients with LLCH of the mandible were treated in a 1-stage procedure with intralesional injection of methylprednisolone. Symptoms of pain were quickly relieved and the swelling receded. Periodic orthopantomogram and computerized tomography after corticosteroid injection revealed continuous regression of mandibular osteolysis and a favorable osseous consolidation in the lesions. CONCLUSIONS: The results of this report suggest that intralesional injection of corticosteroids should be the initial choice of treatment of LLCH of the mandible, especially in children to preserve tooth germs.
Authors: Alex Vargas; Hernán Ramírez; Pablo Ramírez; Camila Foncea; Bernardo Venegas; Paula Astorga Journal: Head Face Med Date: 2016-06-02 Impact factor: 2.151
Authors: Emeline das Neves de Araújo Lima; Eliakim Medeiros Alves de Araújo; Patrícia Teixeira de Oliveira; Ana Miryam Costa de Medeiros Journal: Braz J Otorhinolaryngol Date: 2014-05-23