Literature DB >> 22770211

U1 snRNA rewrites the "script".

Evan C Merkhofer, Tracy L Johnson.   

Abstract

Expression of eukaryotic mRNAs requires the collaboration of a host of RNA processing factors acting upon the transcript. Berg et al. describe how a pre-mRNA splicing factor modulates the activity of the polyadenylation machinery to regulate mRNA length, with important implications for isoform expression in activated neuronal and immune cells.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22770211      PMCID： PMC4088317          DOI： 10.1016/j.cell.2012.06.017

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  9 in total

1.  U1 snRNA associates with TFIIH and regulates transcriptional initiation.

Authors:  Kon Yew Kwek; Shona Murphy; Andre Furger; Benjamin Thomas; William O'Gorman; Hiroshi Kimura; Nick J Proudfoot; Alexandre Akoulitchev
Journal:  Nat Struct Biol       Date:  2002-11

Review 2.  Translational control by changes in poly(A) tail length: recycling mRNAs.

Authors:  Laure Weill; Eulàlia Belloc; Felice-Alessio Bava; Raúl Méndez
Journal:  Nat Struct Mol Biol       Date:  2012-06-05       Impact factor: 15.369

3.  U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase.

Authors:  S I Gunderson; M Polycarpou-Schwarz; I W Mattaj
Journal:  Mol Cell       Date:  1998-01       Impact factor: 17.970

4.  Dynamic histone acetylation is critical for cotranscriptional spliceosome assembly and spliceosomal rearrangements.

Authors:  Felizza Q Gunderson; Evan C Merkhofer; Tracy L Johnson
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-18       Impact factor: 11.205

5.  U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation.

Authors:  Daisuke Kaida; Michael G Berg; Ihab Younis; Mumtaz Kasim; Larry N Singh; Lili Wan; Gideon Dreyfuss
Journal:  Nature       Date:  2010-09-29       Impact factor: 49.962

6.  The human U1A snRNP protein regulates polyadenylation via a direct interaction with poly(A) polymerase.

Authors:  S I Gunderson; K Beyer; G Martin; W Keller; W C Boelens; L W Mattaj
Journal:  Cell       Date:  1994-02-11       Impact factor: 41.582

7.  U1 snRNP determines mRNA length and regulates isoform expression.

Authors:  Michael G Berg; Larry N Singh; Ihab Younis; Qiang Liu; Anna Maria Pinto; Daisuke Kaida; Zhenxi Zhang; Sungchan Cho; Scott Sherrill-Mix; Lili Wan; Gideon Dreyfuss
Journal:  Cell       Date:  2012-07-06       Impact factor: 41.582

8.  The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing.

Authors:  Yehuda Brody; Noa Neufeld; Nicole Bieberstein; Sebastien Z Causse; Eva-Maria Böhnlein; Karla M Neugebauer; Xavier Darzacq; Yaron Shav-Tal
Journal:  PLoS Biol       Date:  2011-01-11       Impact factor: 8.029

9.  A large-scale analysis of mRNA polyadenylation of human and mouse genes.

Authors:  Bin Tian; Jun Hu; Haibo Zhang; Carol S Lutz
Journal:  Nucleic Acids Res       Date:  2005-01-12       Impact factor: 16.971
  9 in total
  5 in total

Review 1.  Noncoding RNAs: Regulators of the Mammalian Transcription Machinery.

Authors:  Tess M Eidem; Jennifer F Kugel; James A Goodrich
Journal:  J Mol Biol       Date:  2016-02-23       Impact factor: 5.469

2.  Improvement of SMN2 pre-mRNA processing mediated by exon-specific U1 small nuclear RNA.

Authors:  Andrea Dal Mas; Malgorzata Ewa Rogalska; Erica Bussani; Franco Pagani
Journal:  Am J Hum Genet       Date:  2014-12-31       Impact factor: 11.025

3.  Identification of a truncated splice variant of IL-18 receptor alpha in the human and rat, with evidence of wider evolutionary conservation.

Authors:  Chris S Booker; David R Grattan
Journal:  PeerJ       Date:  2014-09-11       Impact factor: 2.984

4.  The chromatin remodeling complex Swi/Snf regulates splicing of meiotic transcripts in Saccharomyces cerevisiae.

Authors:  Srivats Venkataramanan; Stephen Douglass; Anoop R Galivanche; Tracy L Johnson
Journal:  Nucleic Acids Res       Date:  2017-07-27       Impact factor: 16.971

5.  Intronic PAH gene mutations cause a splicing defect by a novel mechanism involving U1snRNP binding downstream of the 5' splice site.

Authors:  Ainhoa Martínez-Pizarro; Maja Dembic; Belén Pérez; Brage S Andresen; Lourdes R Desviat
Journal:  PLoS Genet       Date:  2018-04-23       Impact factor: 5.917
  5 in total

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