Literature DB >> 2276856

Immunoreactive corticotropin-releasing hormone levels in brain regions of genetically obese Zucker rats.

S Nakaishi1, Y Nakai, J Fukata, Y Naito, T Usui, H Imura.   

Abstract

The levels of immunoreactive corticotropin-releasing hormone (ir-CRH) were measured in discrete brain regions and pituitary of obese Zucker rats and their lean littermates. Ir-CRH levels were lower in the hypothalamus and neurointermediate pituitary but higher in the striatum and cerebellum of obese Zucker rats than those of lean littermates. These results suggest some abnormalities in the CRH regulating system in obese Zucker rats.

Entities:  

Mesh:

Substances:

Year:  1990        PMID: 2276856

Source DB:  PubMed          Journal:  Int J Obes


  2 in total

1.  Corticotropin-releasing factor-binding protein ligand inhibitor blunts excessive weight gain in genetically obese Zucker rats and rats during nicotine withdrawal.

Authors:  S C Heinrichs; J Lapsansky; D P Behan; R K Chan; P E Sawchenko; M Lorang; N Ling; W W Vale; E B De Souza
Journal:  Proc Natl Acad Sci U S A       Date:  1996-12-24       Impact factor: 11.205

Review 2.  Detrimental effects of chronic hypothalamic-pituitary-adrenal axis activation. From obesity to memory deficits.

Authors:  J Raber
Journal:  Mol Neurobiol       Date:  1998-08       Impact factor: 5.590

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.