| Literature DB >> 22767575 |
Abstract
Jácomo and colleagues advance our understanding of the coagulopathy present in acute promyelocytic leukemia (APL). By means of elegant and intriguing experiments performed in an APL mouse model, they demonstrate that supplementation with L-methionine, an essential amino acid that assists in the metabolism of homocysteine (Hcy), is able to prevent the fibrinolytic abnormalities present in this leukemia.(1)Entities:
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Year: 2012 PMID: 22767575 DOI: 10.1182/blood-2012-05-427427
Source DB: PubMed Journal: Blood ISSN: 0006-4971 Impact factor: 22.113