| Literature DB >> 22765903 |
Stella Peña1, Laura Scarone, Eduardo Manta, Lindsay Stewart, Vanessa Yardley, Simon Croft, Gloria Serra.
Abstract
The synthesis of a Microcystis aeruginosa predicted metabolite analog of aerucyclamide B was performed. This hexacyclopeptide was obtained from three heterocyclic building blocks by a convergent macrocycle-assembly methodology. The compound exhibited good in vitro antiplasmodial activity (IC(50): 0.18 μM, K1, cholorquine resistant strain).Entities:
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Year: 2012 PMID： 22765903 DOI： 10.1016/j.bmcl.2012.06.028
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823