Literature DB >> 22763637

Antimicrobial susceptibility testing, drug resistance mechanisms, and therapy of infections with nontuberculous mycobacteria.

Barbara A Brown-Elliott1, Kevin A Nash, Richard J Wallace.   

Abstract

Within the past 10 years, treatment and diagnostic guidelines for nontuberculous mycobacteria have been recommended by the American Thoracic Society (ATS) and the Infectious Diseases Society of America (IDSA). Moreover, the Clinical and Laboratory Standards Institute (CLSI) has published and recently (in 2011) updated recommendations including suggested antimicrobial and susceptibility breakpoints. The CLSI has also recommended the broth microdilution method as the gold standard for laboratories performing antimicrobial susceptibility testing of nontuberculous mycobacteria. This article reviews the laboratory, diagnostic, and treatment guidelines together with established and probable drug resistance mechanisms of the nontuberculous mycobacteria.

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Year:  2012        PMID： 22763637      PMCID： PMC3416486          DOI： 10.1128/CMR.05030-11

Source DB:  PubMed          Journal:  Clin Microbiol Rev        ISSN： 0893-8512            Impact factor:   26.132


  445 in total

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