OBJECTIVE: Although many Fontan patients undergo pacemaker placement, there are few studies characterizing this population. Our purpose was to compare clinical characteristics, functional status and measures of ventricular performance in Fontan patients with and without a pacemaker. PATIENTS AND DESIGN: The National Heart, Lung, and Blood Institute funded Pediatric Heart Network Fontan Cross-Sectional Study characterized 546 Fontan survivors. Clinical characteristics, medical history and study outcomes (Child Health Questionnaire [CHQ]), echocardiographic evaluation of ventricular function, and exercise testing) were compared between subjects with and without pacemakers. RESULTS: Of 71 subjects with pacemakers (13%), 43/71 (61%) were in a paced rhythm at the time of study enrollment (age 11.9 ± 3.4 years). Pacemaker subjects were older at study enrollment, more likely to have single left ventricles, and taking more medications. There were no differences in age at Fontan or Fontan type between the pacemaker and no pacemaker groups. There were no differences in exercise performance between groups. CHQ physical summary scores were lower in the pacemaker subjects (39.7 ± 14.3 vs. 46.1 ± 11.2, P =.001). Ventricular ejection fraction z-score was also lower (-1.4 ± 1.9 vs. -0.8 ± 2.0, P =.05) in pacemaker subjects. CONCLUSIONS: In our cohort of Fontan survivors, those with a pacemaker have poorer functional status and evidence of decreased ventricular systolic function compared to Fontan survivors without a pacemaker.
OBJECTIVE: Although many Fontan patients undergo pacemaker placement, there are few studies characterizing this population. Our purpose was to compare clinical characteristics, functional status and measures of ventricular performance in Fontan patients with and without a pacemaker. PATIENTS AND DESIGN: The National Heart, Lung, and Blood Institute funded Pediatric Heart Network Fontan Cross-Sectional Study characterized 546 Fontan survivors. Clinical characteristics, medical history and study outcomes (Child Health Questionnaire [CHQ]), echocardiographic evaluation of ventricular function, and exercise testing) were compared between subjects with and without pacemakers. RESULTS: Of 71 subjects with pacemakers (13%), 43/71 (61%) were in a paced rhythm at the time of study enrollment (age 11.9 ± 3.4 years). Pacemaker subjects were older at study enrollment, more likely to have single left ventricles, and taking more medications. There were no differences in age at Fontan or Fontan type between the pacemaker and no pacemaker groups. There were no differences in exercise performance between groups. CHQ physical summary scores were lower in the pacemaker subjects (39.7 ± 14.3 vs. 46.1 ± 11.2, P =.001). Ventricular ejection fraction z-score was also lower (-1.4 ± 1.9 vs. -0.8 ± 2.0, P =.05) in pacemaker subjects. CONCLUSIONS: In our cohort of Fontan survivors, those with a pacemaker have poorer functional status and evidence of decreased ventricular systolic function compared to Fontan survivors without a pacemaker.
Authors: C P Taliercio; R E Vlietstra; M D McGoon; C J Porter; M J Osborn; G K Danielson Journal: J Thorac Cardiovasc Surg Date: 1985-09 Impact factor: 5.209
Authors: Lynn A Sleeper; Page Anderson; Daphne T Hsu; Lynn Mahony; Brian W McCrindle; Stephen J Roth; J Phillip Saul; Richard V Williams; Tal Geva; Steven D Colan; Bernard J Clark Journal: Am Heart J Date: 2006-09 Impact factor: 4.749
Authors: Renee Margossian; Marcy L Schwartz; Ashwin Prakash; Lisa Wruck; Steven D Colan; Andrew M Atz; Timothy J Bradley; Mark A Fogel; Lynne M Hurwitz; Edward Marcus; Andrew J Powell; Beth F Printz; Michael D Puchalski; Jack Rychik; Girish Shirali; Richard Williams; Shi-Joon Yoo; Tal Geva Journal: Am J Cardiol Date: 2009-06-06 Impact factor: 2.778
Authors: Andrew D Blaufox; Lynn A Sleeper; David J Bradley; Roger E Breitbart; Allan Hordof; Ronald J Kanter; Elizabeth A Stephenson; Mario Stylianou; Victoria L Vetter; J Philip Saul Journal: J Thorac Cardiovasc Surg Date: 2008-05-19 Impact factor: 5.209
Authors: M I Cohen; G Wernovsky; V L Vetter; T S Wieand; J W Gaynor; M L Jacobs; T L Spray; L A Rhodes Journal: Circulation Date: 1998-11-10 Impact factor: 29.690
Authors: Page A W Anderson; Lynn A Sleeper; Lynn Mahony; Steven D Colan; Andrew M Atz; Roger E Breitbart; Welton M Gersony; Dianne Gallagher; Tal Geva; Renee Margossian; Brian W McCrindle; Stephen Paridon; Marcy Schwartz; Mario Stylianou; Richard V Williams; Bernard J Clark Journal: J Am Coll Cardiol Date: 2008-07-08 Impact factor: 24.094
Authors: Makoto Mori; Kayoko Shioda; Robert W Elder; Maria A Pernetz; Fred H Rodriguez; Alicia Rangosch; Brian E Kogon; Wendy M Book Journal: Pediatr Cardiol Date: 2016-03-31 Impact factor: 1.655
Authors: Rahul H Rathod; Ashwin Prakash; Yuli Y Kim; Ioannis E Germanakis; Andrew J Powell; Kimberlee Gauvreau; Tal Geva Journal: Circ Cardiovasc Imaging Date: 2014-03-11 Impact factor: 7.792
Authors: Robert W Elder; Nancy M McCabe; Emir Veledar; Brian E Kogon; Maan Jokhadar; Fred H Rodriguez; Michael E McConnell; Wendy M Book Journal: Congenit Heart Dis Date: 2014-08-17 Impact factor: 2.007
Authors: Brian W McCrindle; Victor Zak; Roger E Breitbart; Lynn Mahony; Peter Shrader; Wyman W Lai; Kristin M Burns; Steven D Colan; Richard V Williams; David Goldberg; Kevin D Hill; Svetlana Khaikin; Andrew M Atz Journal: Pediatr Cardiol Date: 2013-11-22 Impact factor: 1.655
Authors: Peter A Zartner; Nathalie Mini; Diana Momcilovic; Martin B Schneider; Sven Dittrich Journal: Thorac Cardiovasc Surg Date: 2021-12-10 Impact factor: 1.827
Authors: Kate H Marshall; Yves D'Udekem; Gary F Sholler; Alexander R Opotowsky; Daniel S J Costa; Louise Sharpe; David S Celermajer; David S Winlaw; Jane W Newburger; Nadine A Kasparian Journal: J Am Heart Assoc Date: 2020-03-16 Impact factor: 5.501