Ephedrine as a marker of intravascular injection in laboring parturients.

Thirty healthy laboring parturients were randomly chosen to receive either normal saline (NS), ephedrine 10 mg (EPH-10), or ephedrine 15 mg (EPH-15) intravenously. Changes in maternal heart rate and blood pressure and fetal heart rate were monitored. A clinically useful and statistically significant (less than 0.001) increase in systolic blood pressure of 10 torr or more occurred in all 10 patients in the EPH-15 group. There was no adverse fetal outcome. Transient fetal tachycardia was seen in three fetuses in the EPH-15 group.

RCT Entities:   Population Interventions Outcomes