Literature DB >> 22754189

Study of serum homocysteine, folic Acid and vitamin b(12) in patients with preeclampsia.

Shahid A Mujawar, Vinayak W Patil, Rekha G Daver.   

Abstract

The present study was carried out to evaluate the occurrence of association between homocysteine, folic acid and vitamin B(12) in patients with preeclampsia. Fifty preeclamptic patients from gynecology ward were studied for estimation of serum homocysteine, folic acid and vitamin B(12) over a period of October 2007 to June 2010. Serum homocysteine and folic acid, and vitamin B(12) were determined by means of Immulite 1000 analyzer. The statistical analysis of study group of preeclampsia compared with normotensive control group, showed significant alterations in serum homocysteine, folic acid and vitamin B(12) concentrations in preeclampsia. Inverse association between serum homocysteine and folic acid, and vitamin B(12) levels were observed in preeclampsia. The present study found hyperhomocysteinemia and deficiency of folic acid and vitamin B(12) along with increased blood pressure as a risk factor for cardiovascular disease (CVD) in preeclampsia.

Entities:  

Keywords:  Folic acid; Homocysteine; Preeclampsia; Vitamin B12

Year:  2011        PMID： 22754189      PMCID： PMC3162959          DOI： 10.1007/s12291-011-0109-3

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN： 0970-1915


  16 in total

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  16 in total

1.  Higher maternal plasma folate, vitamin B12 and homocysteine levels in women with preeclampsia.

Authors:  Hemlata Pisal; Kamini Dangat; Karuna Randhir; Amrita Khaire; Savita Mehendale; Sadhana Joshi
Journal:  J Hum Hypertens       Date:  2019-01-15       Impact factor: 3.012

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Journal:  Eur J Clin Nutr       Date:  2015-01-28       Impact factor: 4.016

3.  Maternal Hypertensive Disorders in Pregnancy and Postpartum Plasma B Vitamin and Homocysteine Profiles in a High-Risk Multiethnic U.S., Population.

Authors:  Bolanle Olapeju; Saifuddin Ahmed; Xiumei Hong; Guoying Wang; Amber Summers; Tina L Cheng; Irina Burd; Xiaobin Wang
Journal:  J Womens Health (Larchmt)       Date:  2020-11-16       Impact factor: 2.681

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Authors:  Zuhier Awan; Sumayah Aljenedil; David S Rosenblatt; Jean Cusson; Brian M Gilfix; Jacques Genest
Journal:  Thromb J       Date:  2014-12-16

5.  A combined supplementation of omega-3 fatty acids and micronutrients (folic acid, vitamin B12) reduces oxidative stress markers in a rat model of pregnancy induced hypertension.

Authors:  Nisha G Kemse; Anvita A Kale; Sadhana R Joshi
Journal:  PLoS One       Date:  2014-11-18       Impact factor: 3.240

6.  The Effect of High Dose Folic Acid throughout Pregnancy on Homocysteine (Hcy) Concentration and Pre-Eclampsia: A Randomized Clinical Trial.

Authors:  Manizheh Sayyah-Melli; Amir Ghorbanihaghjo; Mahasti Alizadeh; Maryamalsadat Kazemi-Shishvan; Morteza Ghojazadeh; Sanam Bidadi
Journal:  PLoS One       Date:  2016-05-11       Impact factor: 3.240

7.  Effects of folic acid supplementation on serum homocysteine and lipoprotein (a) levels during pregnancy.

Authors:  Zohreh Hekmati Azar Mehrabani; Amir Ghorbanihaghjo; Manizheh Sayyah Melli; Maryam Hamzeh-Mivehroud; Nazila Fathi Maroufi; Nasrin Bargahi; Maryam Bannazadeh Amirkhiz; Nadereh Rashtchizadeh
Journal:  Bioimpacts       Date:  2015-12-28

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Authors:  Sang-Min Shim; Yeo-Ul Yun; Yun Sook Kim
Journal:  Obstet Gynecol Sci       Date:  2016-03-16

9.  Prevalence of hyperhomocysteinemia in healthy Indian doctors.

Authors:  Sandesh P Kamdi; Prashant Palkar
Journal:  Bioinformation       Date:  2013-02-21

10.  Severe but Not Moderate Vitamin B12 Deficiency Impairs Lipid Profile, Induces Adiposity, and Leads to Adverse Gestational Outcome in Female C57BL/6 Mice.

Authors:  Shampa Ghosh; Jitendra Kumar Sinha; Uday Kumar Putcha; Manchala Raghunath
Journal:  Front Nutr       Date:  2016-01-22
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