Literature DB >> 22753995

Utilization of the hydroxyalkylation reaction to prepare bis(benzocrown ethers).

Matthew Zielinski1, Adam F Tracy, Douglas A Klumpp.   

Abstract

The hydroxyalkylation reaction has been used to condense benzocrown ethers with various aldehydes and ketones. The condensation reactions are catalyzed by triflic or sulfuric acid. The products from the reactions are bis(benzocrown ethers) and they are formed in good yields (42-98%, 13 examples).

Entities:  

Year:  2012        PMID： 22753995      PMCID： PMC3383084          DOI： 10.1016/j.tetlet.2012.01.049

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


  3 in total

Review 1.  Biomedical potentials of crown ethers: prospective antitumor agents.

Authors:  Marijeta Kralj; Ljerka Tusek-Bozić; Leo Frkanec
Journal:  ChemMedChem       Date:  2008-10       Impact factor: 3.466

2.  Superelectrophilic chemistry of imidazoles.

Authors:  Matthew R Sheets; Ang Li; Edward A Bower; Andrew R Weigel; Matthew P Abbott; Robert M Gallo; Adam A Mitton; Douglas A Klumpp
Journal:  J Org Chem       Date:  2009-03-20       Impact factor: 4.354

3.  BF3-H2O catalyzed hydroxyalkylation of aromatics with aromatic aldehydes and dicarboxaldehydes: efficient synthesis of triarylmethanes, diarylmethylbenzaldehydes, and anthracene derivatives.

Authors:  G K Surya Prakash; Chiradeep Panja; Anton Shakhmin; Eric Shah; Thomas Mathew; George A Olah
Journal:  J Org Chem       Date:  2009-11-20       Impact factor: 4.354
  3 in total
  2 in total

1.  Reactions of ketones with aromatics in acid media. The effect of trifluoromethyl groups and the acidity media. A theoretical study.

Authors:  Ulises Jiménez Castillo; Mikhail G Zolotukhin; Lioudmila Fomina; Daniel Romero Nieto; Lilian Olivera Garza; Serguei Fomine
Journal:  J Mol Model       Date:  2012-10-11       Impact factor: 1.810

2.  Mechanistic aspects of superacid mediated condensation of polyphenols with ketones. Implications for polymer synthesis.

Authors:  Gustavo López; Olivia H Cruz; Lilian I Olvera Garza; Mikhail G Zolotukhin; Serguei Fomine
Journal:  J Mol Model       Date:  2014-10-09       Impact factor: 1.810
  2 in total

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