Literature DB >> 22753683

Lung cancer: new therapeutic targets, new definitions.

James H Finigan, Jeffrey A Kern.   

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Year:  2012        PMID： 22753683      PMCID： PMC3400992          DOI： 10.1164/rccm.201205-0811ED

Source DB:  PubMed          Journal:  Am J Respir Crit Care Med        ISSN： 1073-449X            Impact factor:   21.405


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  13 in total

1.  Endothelial protein C receptor-dependent inhibition of migration of human lymphocytes by protein C involves epidermal growth factor receptor.

Authors:  Clemens Feistritzer; Birgit A Mosheimer; Daniel H Sturn; Matthias Riewald; Josef R Patsch; Christian J Wiedermann
Journal:  J Immunol       Date:  2006-01-15       Impact factor: 5.422

2.  Activated protein C promotes breast cancer cell migration through interactions with EPCR and PAR-1.

Authors:  Lea M Beaulieu; Frank C Church
Journal:  Exp Cell Res       Date:  2006-12-14       Impact factor: 3.905

3.  Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation.

Authors:  James H Finigan; Steven M Dudek; Patrick A Singleton; Eddie T Chiang; Jeffrey R Jacobson; Sara M Camp; Shiu Q Ye; Joe G N Garcia
Journal:  J Biol Chem       Date:  2005-02-14       Impact factor: 5.157

4.  Receptor of activated protein C promotes metastasis and correlates with clinical outcome in lung adenocarcinoma.

Authors:  Iker Antón; Eva Molina; Diego Luis-Ravelo; Carolina Zandueta; Karmele Valencia; Cristina Ormazabal; Susana Martínez-Canarias; Naiara Perurena; María José Pajares; Jackeline Agorreta; Luis M Montuenga; Victor Segura; Ignacio I Wistuba; Javier De Las Rivas; José Hermida; Fernando Lecanda
Journal:  Am J Respir Crit Care Med       Date:  2012-03-29       Impact factor: 21.405

5.  The crystal structure of the endothelial protein C receptor and a bound phospholipid.

Authors:  Vaheh Oganesyan; Natalia Oganesyan; Simon Terzyan; Dongfeng Qu; Zbigniew Dauter; Naomi L Esmon; Charles T Esmon
Journal:  J Biol Chem       Date:  2002-05-28       Impact factor: 5.157

6.  Activated protein C targets CD8+ dendritic cells to reduce the mortality of endotoxemia in mice.

Authors:  Edward Kerschen; Irene Hernandez; Mark Zogg; Shuang Jia; Martin J Hessner; Jose A Fernandez; John H Griffin; Claudia S Huettner; Francis J Castellino; Hartmut Weiler
Journal:  J Clin Invest       Date:  2010-08-16       Impact factor: 14.808

7.  Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers.

Authors:  Hisayuki Shigematsu; Li Lin; Takao Takahashi; Masaharu Nomura; Makoto Suzuki; Ignacio I Wistuba; Kwun M Fong; Huei Lee; Shinichi Toyooka; Nobuyoshi Shimizu; Takehiko Fujisawa; Ziding Feng; Jack A Roth; Joachim Herz; John D Minna; Adi F Gazdar
Journal:  J Natl Cancer Inst       Date:  2005-03-02       Impact factor: 13.506

8.  Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective.

Authors:  Tong Cheng; Dong Liu; John H Griffin; José A Fernández; Francis Castellino; Elliot D Rosen; Kenji Fukudome; Berislav V Zlokovic
Journal:  Nat Med       Date:  2003-02-03       Impact factor: 53.440

9.  Activated protein C induces endothelial cell proliferation by mitogen-activated protein kinase activation in vitro and angiogenesis in vivo.

Authors:  Mitsuhiro Uchiba; Kenji Okajima; Yuichi Oike; Yasuhiro Ito; Kenji Fukudome; Hirotaka Isobe; Toshio Suda
Journal:  Circ Res       Date:  2004-05-27       Impact factor: 17.367

10.  Excision repair cross-complementation group 1 polymorphism predicts overall survival in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy.

Authors:  Wei Zhou; Sarada Gurubhagavatula; Geoffrey Liu; Sohee Park; Donna S Neuberg; John C Wain; Thomas J Lynch; Li Su; David C Christiani
Journal:  Clin Cancer Res       Date:  2004-08-01       Impact factor: 12.531
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