Literature DB >> 22753234

Cinnamic acid/chloroquinoline conjugates as potent agents against chloroquine-resistant Plasmodium falciparum.

Bianca Pérez1, Cátia Teixeira, Jiri Gut, Philip J Rosenthal, José R B Gomes, Paula Gomes.   

Abstract

Cinnamic acid derivatives containing a 4-amino-7-chloroquinoline scaffold (blue) and substituted cinnamoyl building blocks (green) linked through an alkylamine chain (red) were found to have potent (11-59 nM) in vitro activities against erythrocytic chloroquine- resistant Plasmodium falciparum.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID： 22753234     DOI： 10.1002/cmdc.201200257

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


  9 in total

1.  N-cinnamoylated aminoquinolines as promising antileishmanial agents.

Authors:  S Vale-Costa; J Costa-Gouveia; B Pérez; T Silva; C Teixeira; P Gomes; M S Gomes
Journal:  Antimicrob Agents Chemother       Date:  2013-08-05       Impact factor: 5.191

Review 2.  Quinoline-Based Hybrid Compounds with Antimalarial Activity.

Authors:  Xhamla Nqoro; Naki Tobeka; Blessing A Aderibigbe
Journal:  Molecules       Date:  2017-12-19       Impact factor: 4.411

Review 3.  Natural cinnamic acids, synthetic derivatives and hybrids with antimicrobial activity.

Authors:  Juan David Guzman
Journal:  Molecules       Date:  2014-11-25       Impact factor: 4.411

4.  Cinnamoyl-Oxaborole Amides: Synthesis and Their in Vitro Biological Activity.

Authors:  Maureen Gumbo; Richard M Beteck; Tawanda Mandizvo; Ronnett Seldon; Digby F Warner; Heinrich C Hoppe; Michelle Isaacs; Dustin Laming; Christina C Tam; Luisa W Cheng; Nicole Liu; Kirkwood M Land; Setshaba D Khanye
Journal:  Molecules       Date:  2018-08-15       Impact factor: 4.411

Review 5.  Cinnamic Acid Conjugates in the Rescuing and Repurposing of Classical Antimalarial Drugs.

Authors:  Ana Teresa Silva; Clara M Bento; Ana C Pena; Luísa M Figueiredo; Cristina Prudêncio; Luísa Aguiar; Tânia Silva; Ricardo Ferraz; Maria Salomé Gomes; Cátia Teixeira; Paula Gomes
Journal:  Molecules       Date:  2019-12-24       Impact factor: 4.411

6.  Building on Surface-Active Ionic Liquids for the Rescuing of the Antimalarial Drug Chloroquine.

Authors:  Ana Teresa Silva; Lis Lobo; Isabel S Oliveira; Joana Gomes; Cátia Teixeira; Fátima Nogueira; Eduardo F Marques; Ricardo Ferraz; Paula Gomes
Journal:  Int J Mol Sci       Date:  2020-07-27       Impact factor: 5.923

Review 7.  Acridine-Based Antimalarials-From the Very First Synthetic Antimalarial to Recent Developments.

Authors:  Mélanie Fonte; Natália Tassi; Paula Gomes; Cátia Teixeira
Journal:  Molecules       Date:  2021-01-24       Impact factor: 4.411

8.  Chloroquine Analogues as Leads against Pneumocystis Lung Pathogens.

Authors:  Ana Gomes; Ricardo Ferraz; Lauren Ficker; Margaret S Collins; Cristina Prudêncio; Melanie T Cushion; Cátia Teixeira; Paula Gomes
Journal:  Antimicrob Agents Chemother       Date:  2018-10-24       Impact factor: 5.191

9.  Novel Harmicines with Improved Potency against Plasmodium.

Authors:  Marina Marinović; Ivana Perković; Diana Fontinha; Miguel Prudêncio; Jana Held; Lais Pessanha de Carvalho; Tana Tandarić; Robert Vianello; Branka Zorc; Zrinka Rajić
Journal:  Molecules       Date:  2020-09-23       Impact factor: 4.411
  9 in total

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