Literature DB >> 22752778

Therapeutic hypothermia and hypoxic ischemic encephalopathy: opinion and practice of pediatricians in South Africa.

Yaseen Joolay1, Michael C Harrison, Alan R Horn.   

Abstract

BACKGROUND: Recent newborn resuscitation guidelines recommend therapeutic hypothermia (TH) as a treatment to reduce long-term neurological deficit in hypoxic ischemic encephalopathy (HIE) survivors. In South Africa, varied resource constraints may present difficulties in the implementation of TH.
OBJECTIVE: To determine the opinions and practice of South African pediatricians, regarding TH and the management of HIE.
METHODS: We invited 288 South African pediatricians and neonatologists to participate in a web-based survey by e-mail. Practitioners were identified using the Medpages™ database.
RESULTS: Responses were received from 37.8% of the e-mails. Seventy-six percent of respondents stated that hypothermia was either effective or very effective while 4% stated TH was ineffective in the management of HIE. Only 42% of respondents offered TH and a further 9% transferred patients to other units for cooling. Twenty-four percent had not implemented TH nor planned to introduce it into practice in the near future. Ninety-eight percent of respondents stated TH should be the standard of care in tertiary neonatal units.
CONCLUSION: Most pediatricians in South Africa who responded to the survey stated that TH is effective to reduce the neurological deficit in HIE, however, less than half offered it as a treatment.

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Year:  2012        PMID: 22752778     DOI: 10.1515/jpm-2011-0292

Source DB:  PubMed          Journal:  J Perinat Med        ISSN: 0300-5577            Impact factor:   1.901


  3 in total

Review 1.  Therapeutic hypothermia for neonatal encephalopathy in low- and middle-income countries: a systematic review and meta-analysis.

Authors:  Shreela S Pauliah; Seetha Shankaran; Angie Wade; Ernest B Cady; Sudhin Thayyil
Journal:  PLoS One       Date:  2013-03-19       Impact factor: 3.240

2.  Cost-effective therapeutic hypothermia treatment device for hypoxic ischemic encephalopathy.

Authors:  John J Kim; Nathan Buchbinder; Simon Ammanuel; Robert Kim; Erika Moore; Neil O'Donnell; Jennifer K Lee; Ewa Kulikowicz; Soumyadipta Acharya; Robert H Allen; Ryan W Lee; Michael V Johnston
Journal:  Med Devices (Auckl)       Date:  2013-01-03

3.  Thioperamide treats neonatal hypoxic-ischemic encephalopathy by postsynaptic H1 receptors.

Authors:  Feiyong Jia; Lin Du; Yunpeng Hao; Shicheng Liu; Ning Li; Huiyi Jiang
Journal:  Neural Regen Res       Date:  2013-07-05       Impact factor: 5.135

  3 in total

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