Literature DB >> 22752727

The role of TWEAK/Fn14 in cardiac remodeling.

Man-Yi Ren1, Shu-Jian Sui.   

Abstract

The pathophysiological basis of heart failure is cardiac remodeling, a process that comprises structural and functional changes including cardiomyocyte proliferation, hypertrophy, necrosis, apoptosis, autophagy, interstitial fibrosis, contractile dysfunction and ventricular dilatation. Accumulating evidence demonstrate that tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is involved in the process by binding its receptor fibroblast growth factor-inducible molecule 14 (Fn14). In this review, we will discuss the potential role of the TWEAK/Fn14 axis in cardiac remodeling, elucidate its possible mechanisms and explore new therapeutic targets for heart failure.

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Year:  2012        PMID: 22752727     DOI: 10.1007/s11033-012-1867-6

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN: 0301-4851            Impact factor:   2.316


  75 in total

Review 1.  Myocyte proliferation and ventricular remodeling.

Authors:  Annarosa Leri; Jan Kajstura; Piero Anversa
Journal:  J Card Fail       Date:  2002-12       Impact factor: 5.712

2.  Lower plasma soluble TWEAK concentration in patients with newly diagnosed hypertension.

Authors:  Nuri Karadurmus; Serkan Tapan; Mustafa Cakar; Ilkin Naharci; Turgay Celik; Ilker Tasci; Selim Sayin; Tolga Dogan; Turker Turker; M Kemal Erbil; Kenan Saglam
Journal:  Clin Invest Med       Date:  2012-02-01       Impact factor: 0.825

Review 3.  Aldosterone and vascular inflammation.

Authors:  Nancy J Brown
Journal:  Hypertension       Date:  2008-01-02       Impact factor: 10.190

4.  Cardiac overexpression of monocyte chemoattractant protein-1 in transgenic mice prevents cardiac dysfunction and remodeling after myocardial infarction.

Authors:  Hajime Morimoto; Masafumi Takahashi; Atsushi Izawa; Hirohiko Ise; Minoru Hongo; Pappachan E Kolattukudy; Uichi Ikeda
Journal:  Circ Res       Date:  2006-09-21       Impact factor: 17.367

5.  Soluble TWEAK predicts hemodynamic impairment and functional capacity in patients with pulmonary arterial hypertension.

Authors:  Arthur Filusch; Thomas Zelniker; Christian Baumgärtner; Sabine Eschricht; Norbert Frey; Hugo A Katus; Emmanuel Chorianopoulos
Journal:  Clin Res Cardiol       Date:  2011-04-11       Impact factor: 5.460

6.  Early expression of monocyte chemoattractant protein-1 correlates with the onset of isoproterenol-induced cardiac fibrosis in rats with distinct angiotensin-converting enzyme polymorphism.

Authors:  Miguel Copaja Soto; Rodrigo Valenzuela; Adiela Saldaña; María Paz Ocaranza; Jorge E Jalil; Carlos Vio; Paul Lijnen; Gamaliel E Ordenes; Raul Vivar Sanchez; Sergio Lavandero; Guillermo Díaz-Araya
Journal:  J Renin Angiotensin Aldosterone Syst       Date:  2008-09       Impact factor: 1.636

7.  Plasma B-type natriuretic peptide and anti-inflammatory cytokine interleukin-10 levels predict adverse clinical outcome in chronic heart failure patients with depressive symptoms: a 1-year follow-up study.

Authors:  John T Parissis; Dimitrios Farmakis; Maria Nikolaou; Dionysia Birmpa; Vassiliki Bistola; Ioannis Paraskevaidis; Ignatios Ikonomidis; Stavroula Gaitani; Koula Venetsanou; Gerasimos Filippatos; Dimitrios Th Kremastinos
Journal:  Eur J Heart Fail       Date:  2009-10       Impact factor: 15.534

Review 8.  Cardiac remodeling--concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling.

Authors:  J N Cohn; R Ferrari; N Sharpe
Journal:  J Am Coll Cardiol       Date:  2000-03-01       Impact factor: 24.094

Review 9.  Autophagy, redox signaling, and ventricular remodeling.

Authors:  Narasimman Gurusamy; Dipak K Das
Journal:  Antioxid Redox Signal       Date:  2009-08       Impact factor: 8.401

10.  The prognostic value of circulating soluble cell adhesion molecules in patients with chronic congestive heart failure.

Authors:  Wei-Hsian Yin; Jaw-Wen Chen; Hsu-Lung Jen; Meng-Cheng Chiang; Wen-Pin Huang; An-Ning Feng; Shing-Jong Lin; Mason Shing Young
Journal:  Eur J Heart Fail       Date:  2003-08       Impact factor: 15.534

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  10 in total

1.  Chronic intermittent electronic cigarette exposure induces cardiac dysfunction and atherosclerosis in apolipoprotein-E knockout mice.

Authors:  Jorge Espinoza-Derout; Kamrul M Hasan; Xuesi M Shao; Maria C Jordan; Carl Sims; Desean L Lee; Satyesh Sinha; Zena Simmons; Norma Mtume; Yanjun Liu; Kenneth P Roos; Amiya P Sinha-Hikim; Theodore C Friedman
Journal:  Am J Physiol Heart Circ Physiol       Date:  2019-06-07       Impact factor: 4.733

Review 2.  Pay attention to cardiac remodeling in cancer cachexia.

Authors:  Yawen Zheng; Han Chen; Xiaoqing Li; Yuping Sun
Journal:  Support Care Cancer       Date:  2016-04-23       Impact factor: 3.603

3.  Biomeasures and mechanistic modeling highlight PK/PD risks for a monoclonal antibody targeting Fn14 in kidney disease.

Authors:  Xiaoying Chen; Vahid Farrokhi; Pratap Singh; Mireia Fernandez Ocana; Jenil Patel; Lih-Ling Lin; Hendrik Neubert; Joanne Brodfuehrer
Journal:  MAbs       Date:  2017-11-30       Impact factor: 5.857

4.  TWEAK/Fn14, a pathway and novel therapeutic target in myotonic dystrophy.

Authors:  Ramesh S Yadava; Erin P Foff; Qing Yu; Jordan T Gladman; Yun K Kim; Kirti S Bhatt; Charles A Thornton; Timothy S Zheng; Mani S Mahadevan
Journal:  Hum Mol Genet       Date:  2014-12-11       Impact factor: 6.150

5.  TWEAK protects cardiomyocyte against apoptosis in a PI3K/AKT pathway dependent manner.

Authors:  Bin Yang; Ping Yan; Hui Gong; Lin Zuo; Ying Shi; Jian Guo; Rui Guo; Jun Xie; Bao Li
Journal:  Am J Transl Res       Date:  2016-09-15       Impact factor: 4.060

Review 6.  New and emerging biomarkers in left ventricular systolic dysfunction--insight into dilated cardiomyopathy.

Authors:  Deepa M Gopal; Flora Sam
Journal:  J Cardiovasc Transl Res       Date:  2013-04-23       Impact factor: 4.132

7.  A novel llama antibody targeting Fn14 exhibits anti-metastatic activity in vivo.

Authors:  Johannes Trebing; Isabell Lang; Martin Chopra; Steffen Salzmann; Mahan Moshir; Karen Silence; Simone S Riedel; Daniela Siegmund; Andreas Beilhack; Christoph Otto; Harald Wajant
Journal:  MAbs       Date:  2014 Jan-Feb       Impact factor: 5.857

8.  Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts.

Authors:  S Ghavami; R H Cunnington; S Gupta; B Yeganeh; K L Filomeno; D H Freed; S Chen; T Klonisch; A J Halayko; E Ambrose; R Singal; I M C Dixon
Journal:  Cell Death Dis       Date:  2015-03-19       Impact factor: 8.469

9.  The relationship between asymptomatic organ damage, and serum soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) and Interleukin-17A (IL-17A) levels in non-diabetic hypertensive patients.

Authors:  Ihsan Ates; Nihal Ozkayar; Fatma Akyel; Canan Topcuoglu; Serdar Akyel; A Nurdan Barça; Fatih Dede
Journal:  BMC Nephrol       Date:  2014-10-01       Impact factor: 2.388

10.  Soluble Fn14 Is Detected and Elevated in Mouse and Human Kidney Disease.

Authors:  M Nusrat Sharif; Gabriela Campanholle; Eva E Nagiec; Ju Wang; Jameel Syed; Shawn P O'Neil; Yutian Zhan; Karrie Brenneman; Bruce Homer; Hendrik Neubert; Riyez Karim; Nick Pullen; Steven M Evans; Margaret Fleming; Priya Chockalingam; Lih-Ling Lin
Journal:  PLoS One       Date:  2016-05-12       Impact factor: 3.240

  10 in total

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