| Literature DB >> 22751090 |
Huansheng Xu1, B Alexander Yi, Kenneth R Chien.
Abstract
The term "lineage reprogramming" is typically used to describe the conversion of one differentiated somatic cell type into another without transit through a pluripotent intermediate. Two recent reports in Nature demonstrate that such a conversion can be achieved in the heart in situ, and suggest a novel, regenerative approach for the development of cardiac therapeutics.Entities:
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Year: 2012 PMID： 22751090 PMCID： PMC3494388 DOI： 10.1038/cr.2012.101
Source DB: PubMed Journal: Cell Res ISSN： 1001-0602 Impact factor: 25.617