| Literature DB >> 22749880 |
Se E Choe1, Lien T K Nguyen, Jin H Noh, Chang H Kweon, Kondreddy E Reddy, Hong B Koh, Ki Y Chang, Seung W Kang.
Abstract
The complete genomic RNAs of two Korean sacbrood virus (SBV) strains, which infect the honey bee, Apis mellifera, were sequenced. The two sequences (AmSBV-Kor19, AmSBV-Kor21) were distinguished by the presence or absence of a PstI restriction site. These strains comprised of 8784 bp and 8835 bp; contained a single large ORF (179-8707 and 179-8758) encoding 2843 and 2860 amino acids, respectively. Deduced amino acid sequences comparison with some insect viruses showed that regions of helicase, protease and RdRp domains; structural genes were located at the 5' end and non-structural genes at the 3' end. Multiple sequence alignment showed that AmSBV-Kor19 was missing a section between nucleotides 2311 and 2361 (present in SBV-UK and CSBV) but was similar to that of the Korean SBV strain that infects A. cerana (AcSBV-Kor). The differences in the AmSBV-Kor19 strain may be the result of the virus adapting to a different host.Entities:
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Year: 2012 PMID： 22749880 DOI： 10.1016/j.virol.2012.06.008
Source DB: PubMed Journal: Virology ISSN： 0042-6822 Impact factor: 3.616