Literature DB >> 22749396

Translational homeostasis via eIF4E and 4E-BP1.

Alan G Hinnebusch1.   

Abstract

In this issue of Molecular Cell, Yanagiya et al. (2012) describe a regulatory mechanism that couples the abundance of the translational repressor 4E-BP1 with its target eIF4E via proteasomal degradation of 4E-BP1, thus maintaining translation in cells depleted of eIF4E.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID: 22749396     DOI: 10.1016/j.molcel.2012.06.001

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  11 in total

1.  The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha.

Authors:  Mi-Na Hong; Ky-Youb Nam; Kyung Kon Kim; So-Young Kim; InKi Kim
Journal:  Cell Stress Chaperones       Date:  2016-02-12       Impact factor: 3.667

2.  VP1 and VP3 Are Required and Sufficient for Translation Initiation of Uncapped Infectious Bursal Disease Virus Genomic Double-Stranded RNA.

Authors:  Chengjin Ye; Yu Wang; Enli Zhang; Xinpeng Han; Zhaoli Yu; Hebin Liu
Journal:  J Virol       Date:  2018-01-02       Impact factor: 5.103

3.  Regulation of transient receptor potential cation channel subfamily V1 protein synthesis by the phosphoinositide 3-kinase/Akt pathway in colonic hypersensitivity.

Authors:  Shanwei Shen; Hamad W Al-Thumairy; Fiza Hashmi; Li-Ya Qiao
Journal:  Exp Neurol       Date:  2017-06-03       Impact factor: 5.330

4.  PC-1/PrLZ confers resistance to rapamycin in prostate cancer cells through increased 4E-BP1 stability.

Authors:  Lan Yu; Zeng-Fu Shang; Jian Wang; Hongtao Wang; Fang Huang; Zhe Zhang; Ying Wang; Jianguang Zhou; Shanhu Li
Journal:  Oncotarget       Date:  2015-08-21

5.  The alveolate translation initiation factor 4E family reveals a custom toolkit for translational control in core dinoflagellates.

Authors:  Grant D Jones; Ernest P Williams; Allen R Place; Rosemary Jagus; Tsvetan R Bachvaroff
Journal:  BMC Evol Biol       Date:  2015-02-10       Impact factor: 3.260

Review 6.  mTOR co-targeting strategies for head and neck cancer therapy.

Authors:  Zhiyong Wang; Juan Callejas Valera; Xuefeng Zhao; Qianming Chen; J Silvio Gutkind
Journal:  Cancer Metastasis Rev       Date:  2017-09       Impact factor: 9.264

7.  Individual Copy Number of Ribosomal Genes as a Factor of Mental Retardation and Autism Risk and Severity.

Authors:  Lev Porokhovnik
Journal:  Cells       Date:  2019-09-26       Impact factor: 6.600

8.  Ribosomal Biogenesis and Translational Flux Inhibition by the Selective Inhibitor of Nuclear Export (SINE) XPO1 Antagonist KPT-185.

Authors:  Yoko Tabe; Kensuke Kojima; Shinichi Yamamoto; Kazumasa Sekihara; Hiromichi Matsushita; Richard Eric Davis; Zhiqiang Wang; Wencai Ma; Jo Ishizawa; Saiko Kazuno; Michael Kauffman; Sharon Shacham; Tsutomu Fujimura; Takashi Ueno; Takashi Miida; Michael Andreeff
Journal:  PLoS One       Date:  2015-09-04       Impact factor: 3.240

9.  High Inorganic Phosphate Intake Promotes Tumorigenesis at Early Stages in a Mouse Model of Lung Cancer.

Authors:  Somin Lee; Ji-Eun Kim; Seong-Ho Hong; Ah-Young Lee; Eun-Jung Park; Hwi Won Seo; Chanhee Chae; Philip Doble; David Bishop; Myung-Haing Cho
Journal:  PLoS One       Date:  2015-08-18       Impact factor: 3.240

10.  Interferon-α enhances the susceptibility of renal cell carcinoma to rapamycin by suppressing mTOR activity.

Authors:  Xiao Han; Donghao Shang; Tiandong Han; Xiuhong Xu; Ye Tian
Journal:  Exp Ther Med       Date:  2014-04-25       Impact factor: 2.447

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