Literature DB >> 22747797

Presence of obsessive compulsive symptoms in first-episode schizophrenia or related disorders is associated with subjective well-being and quality of life.

Lieuwe de Haan1, Bouke Sterk, Renate van der Valk.   

Abstract

AIM: The study aims to evaluate whether the presence of obsessive compulsive symptoms (OCS) in first-episode schizophrenia patients is associated with subjective well-being or quality of life.
METHODS: This study used a cross-sectional study of consecutively diagnosed patients with a first episode of schizophrenia or related disorder.
RESULTS: There were 23 out of 198 (12%) consecutively assessed patients that reported co-morbid OCS. Co-morbid OCS were associated with a lower mean total score on a subjective well-being scale (P ≤ 0.001), especially on the social integration subscale (P = 0.002) and emotional regulation subscale (P = 0.008), and lower scores on subjective aspects of quality of life (P = 0.043), especially concerning mental health (P = 0.001) and physical health (P = 0.002).
CONCLUSION: These results support the clinical relevance of OCS co-morbidity in schizophrenia or related disorders and the need for research into specific interventions.
© 2012 Wiley Publishing Asia Pty Ltd.

Entities:  

Keywords:  obsessive compulsive symptom; quality of life; schizophrenia; subjective experience

Mesh:

Year:  2012        PMID: 22747797     DOI: 10.1111/j.1751-7893.2012.00377.x

Source DB:  PubMed          Journal:  Early Interv Psychiatry        ISSN: 1751-7885            Impact factor:   2.732


  7 in total

Review 1.  Anxiety in Patients with Schizophrenia: Epidemiology and Management.

Authors:  Henk Temmingh; Dan J Stein
Journal:  CNS Drugs       Date:  2015       Impact factor: 5.749

2.  Stable cognitive deficits in schizophrenia patients with comorbid obsessive-compulsive symptoms: a 12-month longitudinal study.

Authors:  Frederike Schirmbeck; Franziska Rausch; Susanne Englisch; Sarah Eifler; Christine Esslinger; Andreas Meyer-Lindenberg; Mathias Zink
Journal:  Schizophr Bull       Date:  2012-10-27       Impact factor: 9.306

3.  Comorbid obsessive-compulsive symptoms in schizophrenia: contributions of pharmacological and genetic factors.

Authors:  Frederike Schirmbeck; Mathias Zink
Journal:  Front Pharmacol       Date:  2013-08-09       Impact factor: 5.810

4.  Obsessive-compulsive symptoms and overall psychopathology in psychotic disorders: longitudinal assessment of patients and siblings.

Authors:  Frederike Schirmbeck; Marije Swets; Carin J Meijer; Mathias Zink; Lieuwe de Haan
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2016-12-17       Impact factor: 5.270

5.  A cross sectional study of impact and clinical risk factors of antipsychotic-induced OCD.

Authors:  Marjan Biria; Fiona-Xiaofei Huang; Yulia Worbe; Naomi A Fineberg; Trevor W Robbins; Emilio Fernandez-Egea
Journal:  Eur Neuropsychopharmacol       Date:  2019-07-11       Impact factor: 4.600

6.  Reduced activity and connectivity of left amygdala in patients with schizophrenia treated with clozapine or olanzapine.

Authors:  Daniela Mier; Frederike Schirmbeck; Gabriela Stoessel; Christine Esslinger; Franziska Rausch; Susanne Englisch; Sarah Eisenacher; Lieuwe de Haan; Andreas Meyer-Lindenberg; Peter Kirsch; Mathias Zink
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2018-12-11       Impact factor: 5.270

Review 7.  Comorbid Obsessive-Compulsive Symptoms in Schizophrenia: Insight into Pathomechanisms Facilitates Treatment.

Authors:  Mathias Zink
Journal:  Adv Med       Date:  2014-06-11
  7 in total

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