Literature DB >> 22747704

Case report of atopic dermatitis with refractory pruritus markedly improved with the novel use of clonidine and trimeprazine.

Annie Genois1, Margaret Haig, Anne Des Roches, Alain Sirard, Sylvie Le May, Catherine C McCuaig.   

Abstract

We report a 6-year-old boy with severe atopic dermatitis and refractory pruritus. The novel use of clonidine, an adrenergic agonist, along with trimeprazine, led to dramatic improvement. This represents the first case report of clonidine's effect in relieving pruritus in atopic dermatitis.
© 2012 Wiley Periodicals, Inc.

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Year:  2012        PMID： 22747704     DOI： 10.1111/j.1525-1470.2012.01756.x

Source DB:  PubMed          Journal:  Pediatr Dermatol        ISSN： 0736-8046            Impact factor:   1.588


  3 in total

1.  Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in mice.

Authors:  Alexandra Kuznetsova; Yue Yu; Jennifer Hollister-Lock; Lynn Opare-Addo; Aldo Rozzo; Marianna Sadagurski; Lisa Norquay; Jessica E Reed; Ilham El Khattabi; Susan Bonner-Weir; Gordon C Weir; Arun Sharma; Morris F White
Journal:  JCI Insight       Date:  2016-03-17

Review 2.  Sleep Disturbances and Atopic Dermatitis: Relationships, Methods for Assessment, and Therapies.

Authors:  Fatima Bawany; Carrie A Northcott; Lisa A Beck; Wilfred R Pigeon
Journal:  J Allergy Clin Immunol Pract       Date:  2020-12-13

3.  Detoxification combining fasting with fluid therapy for refractory cases of severe atopic dermatitis.

Authors:  Kyu Seok Kim; Hae Jeong Nam
Journal:  Evid Based Complement Alternat Med       Date:  2013-08-06       Impact factor: 2.629
  3 in total

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