Literature DB >> 22746007

[Epidemiology of mitral valve disease in pediatrics: a Lebanese study].

Ghassan Chehab1, Issam El-Rassi, Imad Chokor, Chawke Hammoud, Zakhia Saliba.   

Abstract

OBJECTIVES: To study the incidence, etiology, clinical signs and treatment of children with mitral valve disease in Lebanon. PATIENTS AND METHODS: This is a retrospective study on a period of 9 years (between May 1, 1999 and April 30, 2008), including a group of children with congenital and acquired heart disease, consecutively enrolled in the National Register of Pediatric and Congenital Heart Disease, Lebanese Society of Cardiology.
RESULTS: 2586 new patients aged 0-18 years were recorded. Among them, 128 (4.9%) had mitral disease. The causes were congenital in 65% of the cases (28% were associated with other congenital heart anomalies, especially a double outlet right ventricle) and acquired in 35% of the cases (91% were secondary to rheumatic fever). The diagnosis of the disease was fortuitous in 24% of the cases, and a murmur was discovered on auscultation in 53% of the cases. The majority of children showed mitral regurgitation (86%). The regurgitation was severe in 12% of the cases. Half of the children received medical or surgical treatment. The mortality of this disease reached 2%.
CONCLUSION: Congenital anomalies of the mitral valve are the most common cause of mitral regurgitation in children. Rheumatic disease remains another important cause of mitral disease in Lebanon. A high index of suspicion must exist, since the vast majority of diseases are found fortuitously or during simple auscultation.

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Year:  2011        PMID: 22746007

Source DB:  PubMed          Journal:  J Med Liban        ISSN: 0023-9852


  2 in total

1.  Mitral Regurgitation and Serum N-Terminal Pro-Brain Natriuretic Peptide Levels in Children: A Modification of Adult Criteria.

Authors:  Elif Erolu; Figen Akalin
Journal:  Tex Heart Inst J       Date:  2022-07-01

Review 2.  Mechanotransduction Mechanisms in Mitral Valve Physiology and Disease Pathogenesis.

Authors:  Leah A Pagnozzi; Jonathan T Butcher
Journal:  Front Cardiovasc Med       Date:  2017-12-22
  2 in total

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