Literature DB >> 2274516

[Study of genetic markers in families of patients with tuberculosis].

A Kh Rakhimov, L E Pospelov.   

Abstract

The article deals with findings of the study of HLA-genotype influence on tuberculosis susceptibility in 26 families with tuberculosis patients. It was found that sensitivity to tuberculosis in the examined families is associated with HLA-DR2 antigen. Segregation analyses conducted in the families of patients with tuberculosis revealed a correlation between the sensitivity to tuberculosis and inheritance of certain HLA haplotypes from the affected parents to their children with tuberculosis.

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Year:  1990        PMID: 2274516

Source DB:  PubMed          Journal:  Probl Tuberk        ISSN: 0032-9533


  1 in total

1.  Biological individuality and disease. From Garrod's Chemical Individuality to HLA associated diseases.

Authors:  G R Burgio
Journal:  Acta Biotheor       Date:  1993-09       Impact factor: 1.774

  1 in total

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