| Literature DB >> 22744889 |
Bao-Min Fan1, Qing-jing Yang, Jun Hu, Cai-ling Fan, Si-feng Li, Lu Yu, Chao Huang, Wing Wai Tsang, Fuk Yee Kwong.
Abstract
Across bonds: The first successful iridium-catalyzed asymmetric hydroalkynylation of nonpolar alkenes with good to excellent enantioselectivity is described (see scheme; cod = 1,5-cyclooctadiene, DCE = 1,2-dichloroethane). This catalytic system exhibits good functional group compatibility as NH(2), OH, Br, F, and SiMe(3) groups remain intact during the reaction.Entities:
Mesh：
Substances：
Year: 2012 PMID： 22744889 DOI： 10.1002/anie.201203107
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336