BACKGROUND: This report summarizes a single center's experience with liver transplantation (LT) performed for secondary biliary cirrhosis resulting from iatrogenic bile duct injury (BDI) sustained during cholecystectomy. MATERIAL/ METHODS: Secondary biliary cirrhosis was the indication for LT in 5 (1.7%) out of 300 LTs performed in our center between Feb 2002 and April 2011. We analyzed the medical history of the patients, perioperative course and outcome following LT. RESULTS: The BDI was classified as Strasberg A in 1 case, B in two cases, and E in 2 cases. There was no hepatic arterial or portal vein injury in any patient. All of the surgical repairs prior to the development of cirrhosis were performed in general surgical units. The median time between BDI and listing the patient for LT was 11 years. The cadaveric whole-organ LT was done in all patients using the Piggy-Back technique. All patients are alive with a median follow-up of 53 months. CONCLUSIONS: Liver transplantation in patients with secondary biliary cirrhosis appears to result from a series of inadequate multiple surgical repairs following BDI. The immediate referral of such patients to centers with bile duct surgery experience is crucial.
BACKGROUND: This report summarizes a single center's experience with liver transplantation (LT) performed for secondary biliary cirrhosis resulting from iatrogenic bile duct injury (BDI) sustained during cholecystectomy. MATERIAL/ METHODS:Secondary biliary cirrhosis was the indication for LT in 5 (1.7%) out of 300 LTs performed in our center between Feb 2002 and April 2011. We analyzed the medical history of the patients, perioperative course and outcome following LT. RESULTS: The BDI was classified as Strasberg A in 1 case, B in two cases, and E in 2 cases. There was no hepatic arterial or portal vein injury in any patient. All of the surgical repairs prior to the development of cirrhosis were performed in general surgical units. The median time between BDI and listing the patient for LT was 11 years. The cadaveric whole-organ LT was done in all patients using the Piggy-Back technique. All patients are alive with a median follow-up of 53 months. CONCLUSIONS: Liver transplantation in patients with secondary biliary cirrhosis appears to result from a series of inadequate multiple surgical repairs following BDI. The immediate referral of such patients to centers with bile duct surgery experience is crucial.
Authors: Andrea Lauterio; Riccardo De Carlis; Stefano Di Sandro; Fabio Ferla; Vincenzo Buscemi; Luciano De Carlis Journal: World J Hepatol Date: 2017-08-28
Authors: Jerzy Lubikowski; Bernard Piotuch; Anna Stadnik; Marta Przedniczek; Piotr Remiszewski; Piotr Milkiewicz; Michael A Silva; Maciej Wojcicki Journal: BMC Surg Date: 2019-11-06 Impact factor: 2.102
Authors: Peter Tsaparas; Nikolaos Machairas; Victoria Ardiles; Marek Krawczyk; Damiano Patrono; Umberto Baccarani; Umberto Cillo; Einar Martin Aandahl; Christian Cotsoglou; Johana Leiva Espinoza; Rodrigo Sanchez Claría; Ioannis D Kostakis; Aksel Foss; Vincenzo Mazzaferro; Eduardo de Santibañes; Georgios C Sotiropoulos Journal: Ann Gastroenterol Date: 2020-10-02