Literature DB >> 22743345

Hierarchical organization and regulation of the hematopoietic stem cell osteoblastic niche.

Hongxu Wang1, Penghui Zhang, Lin Liu, Lin Zou.   

Abstract

Hematopoietic stem cells (HSCs) are characterized with long-term self-renewal and multi-lineage differentiation. HSCs preferentially reside in osteoblastic niche that is hierarchically organized so as to exactly regulate HSCs properties and maintain organism hematopoietic homeostasis. Hematopoietic stem cell-mesenchymal stem cell pairings share stem cell niches in adult bone marrow under immune-humoral-neural regulation. Here, we review the hierarchical HSC osteoblastic niche in terms of its localization, composition, function, and multi-layer regulation systems.
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Mesh：

Year:  2012        PMID： 22743345     DOI： 10.1016/j.critrevonc.2012.05.004

Source DB:  PubMed          Journal:  Crit Rev Oncol Hematol        ISSN： 1040-8428            Impact factor:   6.312


  5 in total

1.  SHIP1 regulates MSC numbers and their osteolineage commitment by limiting induction of the PI3K/Akt/β-catenin/Id2 axis.

Authors:  Sonia Iyer; Dennis R Viernes; John D Chisholm; Bryan S Margulies; William G Kerr
Journal:  Stem Cells Dev       Date:  2014-07-03       Impact factor: 3.272

Review 2.  Stem cells and cancer stem-like cells in endocrine tissues.

Authors:  Ricardo V Lloyd; Heather Hardin; Celina Montemayor-Garcia; Fabio Rotondo; Luis V Syro; Eva Horvath; Kalman Kovacs
Journal:  Endocr Pathol       Date:  2013-03       Impact factor: 3.943

Review 3.  MicroRNAs in the control of metastatic bone disease.

Authors:  Gillian Browne; Hanna Taipaleenmäki; Gary S Stein; Janet L Stein; Jane B Lian
Journal:  Trends Endocrinol Metab       Date:  2014-05-05       Impact factor: 12.015

Review 4.  Interleukin-17 and its implication in the regulation of differentiation and function of hematopoietic and mesenchymal stem cells.

Authors:  Slavko Mojsilović; Aleksandra Jauković; Juan F Santibañez; Diana Bugarski
Journal:  Mediators Inflamm       Date:  2015-04-27       Impact factor: 4.711

Review 5.  P53 functional abnormality in mesenchymal stem cells promotes osteosarcoma development.

Authors:  T Velletri; N Xie; Y Wang; Y Huang; Q Yang; X Chen; Q Chen; P Shou; Y Gan; G Cao; G Melino; Y Shi
Journal:  Cell Death Dis       Date:  2016-01-21       Impact factor: 8.469
  5 in total

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