Literature DB >> 2274024

Functional analysis of ARGRI and ARGRIII regulatory proteins involved in the regulation of arginine metabolism in Saccharomyces cerevisiae.

H F Qiu1, E Dubois, P Broën, F Messenguy.   

Abstract

We present here a functional analysis of ARGRI and ARGRIII regulatory proteins which are involved together with ARGRII in specific regulation of arginine anabolic and catabolic pathways. Unlike ARGRII, ARGRI and ARGRIII have no transcriptional activation capacity. The first 60 amino acids of ARGRI (out of 177) are dispensable for its activity. The functional domain of the protein is located in the region of homology with MCM1 and SRF proteins. ARGRIII contains in its C-terminal portion a stretch of 17 aspartate residues which are indispensable for arginine regulation. Gene disruption of the ARGRIII gene impairs the growth of the mutant on rich medium, showing that ARGRIII has a pleiotropic role in the cell.

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Year:  1990        PMID: 2274024     DOI: 10.1007/bf00633817

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN: 0026-8925


  24 in total

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Authors:  F Messenguy; E Dubois
Journal:  Mol Gen Genet       Date:  1988-01
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  19 in total

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Authors:  Stephen B Shears
Journal:  Biochem J       Date:  2004-01-15       Impact factor: 3.857

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Authors:  H F Qui; E Dubois; F Messenguy
Journal:  Mol Cell Biol       Date:  1991-04       Impact factor: 4.272

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Authors:  E Dubois; F Messenguy
Journal:  Mol Cell Biol       Date:  1991-04       Impact factor: 4.272

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Journal:  Mol Cell Biol       Date:  1992-01       Impact factor: 4.272

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Authors:  Elia M Crisucci; Karen M Arndt
Journal:  Eukaryot Cell       Date:  2011-04-15

6.  Inositol phosphate multikinase dependent transcriptional control.

Authors:  Ace J Hatch; Audrey R Odom; John D York
Journal:  Adv Biol Regul       Date:  2017-03-21

7.  Pleiotropic function of ArgRIIIp (Arg82p), one of the regulators of arginine metabolism in Saccharomyces cerevisiae. Role in expression of cell-type-specific genes.

Authors:  E Dubois; F Messenguy
Journal:  Mol Gen Genet       Date:  1994-05-10

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Journal:  Mol Cell Biol       Date:  1996-10       Impact factor: 4.272

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Authors:  Adil Jamai; Evelyne Dubois; Andrew K Vershon; Francine Messenguy
Journal:  Mol Cell Biol       Date:  2002-08       Impact factor: 4.272

10.  Tripartite structure of the Saccharomyces cerevisiae arginase (CAR1) gene inducer-responsive upstream activation sequence.

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Journal:  J Bacteriol       Date:  1992-11       Impact factor: 3.490

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