Literature DB >> 22739962

Posttranslational modifications in connexins and pannexins.

Scott R Johnstone1, Marie Billaud, Alexander W Lohman, Evan P Taddeo, Brant E Isakson.   

Abstract

Posttranslational modification is a common cellular process that is used by cells to ensure a particular protein function. This can happen in a variety of ways, e.g., from the addition of phosphates or sugar residues to a particular amino acid, ensuring proper protein life cycle and function. In this review, we assess the evidence for ubiquitination, glycosylation, phosphorylation, S-nitrosylation as well as other modifications in connexins and pannexin proteins. Based on the literature, we find that posttranslational modifications are an important component of connexin and pannexin regulation.

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Year:  2012        PMID： 22739962      PMCID： PMC3954810          DOI： 10.1007/s00232-012-9453-3

Source DB:  PubMed          Journal:  J Membr Biol        ISSN： 0022-2631            Impact factor:   1.843


  168 in total

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Authors:  D Voges; P Zwickl; W Baumeister
Journal:  Annu Rev Biochem       Date:  1999       Impact factor: 23.643

2.  Casein kinase 1 regulates connexin-43 gap junction assembly.

Authors:  Cynthia D Cooper; Paul D Lampe
Journal:  J Biol Chem       Date:  2002-09-20       Impact factor: 5.157

3.  Lipid rafts prepared by different methods contain different connexin channels, but gap junctions are not lipid rafts.

Authors:  Darren Locke; Jade Liu; Andrew L Harris
Journal:  Biochemistry       Date:  2005-10-04       Impact factor: 3.162

Review 4.  The role of the proteasome in heart disease.

Authors:  Yi-Fan Li; Xuejun Wang
Journal:  Biochim Biophys Acta       Date:  2010-09-15

Review 5.  Gap junctions: the "kiss of death" and the "kiss of life".

Authors:  A F Andrade-Rozental; R Rozental; M G Hopperstad; J K Wu; F D Vrionis; D C Spray
Journal:  Brain Res Brain Res Rev       Date:  2000-04

6.  Connexin membrane protein biosynthesis is influenced by polypeptide positioning within the translocon and signal peptidase access.

Authors:  M M Falk; N B Gilula
Journal:  J Biol Chem       Date:  1998-04-03       Impact factor: 5.157

7.  Nitric oxide specifically reduces the permeability of Cx37-containing gap junctions to small molecules.

Authors:  Petra Kameritsch; Natascha Khandoga; Wolfram Nagel; Christina Hundhausen; Darcy Lidington; Ulrich Pohl
Journal:  J Cell Physiol       Date:  2005-04       Impact factor: 6.384

8.  Role for nitric oxide in permeability of hippocampal neuronal hemichannels during oxygen glucose deprivation.

Authors:  Le Zhang; Tongle Deng; Yiguo Sun; Kezhou Liu; Yi Yang; Xiaoxiang Zheng
Journal:  J Neurosci Res       Date:  2008-08-01       Impact factor: 4.164

9.  Multimeric connexin interactions prior to the trans-Golgi network.

Authors:  J Das Sarma; R A Meyer; F Wang; V Abraham; C W Lo; M Koval
Journal:  J Cell Sci       Date:  2001-11       Impact factor: 5.285

10.  Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC.

Authors:  Joell L Solan; Lucrecia Marquez-Rosado; Paul L Sorgen; Perry J Thornton; Philip R Gafken; Paul D Lampe
Journal:  J Cell Biol       Date:  2007-12-17       Impact factor: 10.539
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  47 in total

1.  Nutrient Starvation Decreases Cx43 Levels and Limits Intercellular Communication in Primary Bovine Corneal Endothelial Cells.

Authors:  Catheleyne D'hondt; Jegan Iyyathurai; Kirsten Welkenhuyzen; Bernard Himpens; Luc Leybaert; Geert Bultynck
Journal:  J Membr Biol       Date:  2016-02-12       Impact factor: 1.843

Review 2.  Proteins and mechanisms regulating gap-junction assembly, internalization, and degradation.

Authors:  Anastasia F Thévenin; Tia J Kowal; John T Fong; Rachael M Kells; Charles G Fisher; Matthias M Falk
Journal:  Physiology (Bethesda)       Date:  2013-03

Review 3.  Regulation of cellular communication by signaling microdomains in the blood vessel wall.

Authors:  Marie Billaud; Alexander W Lohman; Scott R Johnstone; Lauren A Biwer; Stephanie Mutchler; Brant E Isakson
Journal:  Pharmacol Rev       Date:  2014-03-26       Impact factor: 25.468

4.  Diverse post-translational modifications of the pannexin family of channel-forming proteins.

Authors:  Silvia Penuela; Alexander W Lohman; Wesley Lai; Laszlo Gyenis; David W Litchfield; Brant E Isakson; Dale W Laird
Journal:  Channels (Austin)       Date:  2014-01-13       Impact factor: 2.581

5.  Cardiac myocyte alternans in intact heart: Influence of cell-cell coupling and β-adrenergic stimulation.

Authors:  Karin P Hammer; Senka Ljubojevic; Crystal M Ripplinger; Burkert M Pieske; Donald M Bers
Journal:  J Mol Cell Cardiol       Date:  2015-03-28       Impact factor: 5.000

Review 6.  Connexins in the Heart: Regulation, Function and Involvement in Cardiac Disease.

Authors:  Antonio Rodríguez-Sinovas; Jose Antonio Sánchez; Laura Valls-Lacalle; Marta Consegal; Ignacio Ferreira-González
Journal:  Int J Mol Sci       Date:  2021-04-23       Impact factor: 5.923

7.  Carbon monoxide (CO) is a novel inhibitor of connexin hemichannels.

Authors:  Carmen G León-Paravic; Vania A Figueroa; Diego J Guzmán; Carlos F Valderrama; Antonio A Vallejos; Mariana C Fiori; Guillermo A Altenberg; Luis Reuss; Mauricio A Retamal
Journal:  J Biol Chem       Date:  2014-11-10       Impact factor: 5.157

Review 8.  Degradation of connexins and gap junctions.

Authors:  Matthias M Falk; Rachael M Kells; Viviana M Berthoud
Journal:  FEBS Lett       Date:  2014-01-30       Impact factor: 4.124

9.  Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity.

Authors:  Nicholas L Weilinger; Alexander W Lohman; Brooke D Rakai; Evelyn M M Ma; Jennifer Bialecki; Valentyna Maslieieva; Travis Rilea; Mischa V Bandet; Nathan T Ikuta; Lucas Scott; Michael A Colicos; G Campbell Teskey; Ian R Winship; Roger J Thompson
Journal:  Nat Neurosci       Date:  2016-02-08       Impact factor: 24.884

Review 10.  Trafficking highways to the intercalated disc: new insights unlocking the specificity of connexin 43 localization.

Authors:  Shan-Shan Zhang; Robin M Shaw
Journal:  Cell Commun Adhes       Date:  2014-02
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