Literature DB >> 22739037

Effects of combined phacoemulsification and viscogoniosynechialysis versus trabeculectomy in patients with primary angle-closure glaucoma and coexisting cataract.

Yating Tang1, Shaohong Qian, Jiajian Wang, Jing Yao, Jianjiang Xu, Lina Cheng, Chuandi Zhou.   

Abstract

AIMS: To compare the effectiveness of combined phacoemulsification and viscogoniosynechialysis versus trabeculectomy alone in primary angle-closure glaucoma (PACG) with a coexisting cataract.
METHODS: Thirty-nine Chinese patients (39 eyes) were retrospectively analyzed: 19 patients underwent combined phacoemulsification and viscogoniosynechialysis (group 1), and 20 underwent trabeculectomy (group 2). In both groups, the intraocular pressure (IOP), the number of antiglaucoma medications, the best corrected visual acuity (BCVA), the central anterior chamber depth (ACD), the synechial/apposition angle closure (SAC), and the success rates were assessed.
RESULTS: The median follow-up periods were similar for both groups (10 months). At the last follow-up, the mean IOP was 14.09 ± 6.89 mm Hg and the mean number of antiglaucoma medications was 0.36 ± 0.59 in group 1; in group 2, the mean IOP was 16.48 ± 4.74 mm Hg (p = 0.066) and the mean number of antiglaucoma medications was 1.05 ± 0.99 (p = 0.025). In terms of the mean central ACD and the mean SAC, there were significant differences between the groups (p = 0.0000, respectively). Kaplan-Meier analysis revealed that the cumulative probability of success in group 1 was higher than that in group 2 (p = 0.0051).
CONCLUSION: Compared to trabeculectomy, combined phacoemulsification and viscogoniosynechialysis resulted in a lower requirement for glaucomatous medications, a greater improvement in BCVA, and a higher cumulative probability that treatment would be successful among patients with PACG and coexisting cataracts.
Copyright © 2012 S. Karger AG, Basel.

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Year:  2012        PMID: 22739037     DOI: 10.1159/000338241

Source DB:  PubMed          Journal:  Ophthalmologica        ISSN: 0030-3755            Impact factor:   3.250


  3 in total

1.  Schlemm's canal expands after trabeculectomy in patients with primary angle-closure glaucoma.

Authors:  Jiaxu Hong; Yujing Yang; Anji Wei; Sophie X Deng; Xiangmei Kong; Junyi Chen; Michaël J A Girard; Jean Martial Mari; Jianjiang Xu; Xinghuai Sun
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-08-12       Impact factor: 4.799

2.  Managing Primary Angle Closure Glaucoma - The Role of Lens Extraction in this Era.

Authors:  Nafees Baig; Ka-Wai Kam; Clement C Y Tham
Journal:  Open Ophthalmol J       Date:  2016-02-29

Review 3.  The management of patients with cataracts and medically uncontrolled glaucoma.

Authors:  Rahat Husain
Journal:  Med Hypothesis Discov Innov Ophthalmol       Date:  2014
  3 in total

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