OBJECTIVE: To solve the difficult in the active compounds screening from traditional Chinese medicines (TCM). METHOD: According to preliminary lab results and related literature, systematic analysis of the high-throughput technology was made. RESULT: Technologies of rapid preparation, high-throughput screening and biochip, together with the thought of drug target network, will contribute to TCM research on active ingredients screening, toxic components exclusion and molecular mechanisms. They are key technologies and ideas for modernization of TCM and research of TCM network pharmacology. CONCLUSION: High throughput technology and network pharmacology-related technologies will provide new ideas and key methods for active compounds screening from TCM.
OBJECTIVE: To solve the difficult in the active compounds screening from traditional Chinese medicines (TCM). METHOD: According to preliminary lab results and related literature, systematic analysis of the high-throughput technology was made. RESULT: Technologies of rapid preparation, high-throughput screening and biochip, together with the thought of drug target network, will contribute to TCM research on active ingredients screening, toxic components exclusion and molecular mechanisms. They are key technologies and ideas for modernization of TCM and research of TCM network pharmacology. CONCLUSION: High throughput technology and network pharmacology-related technologies will provide new ideas and key methods for active compounds screening from TCM.
Authors: Tao Huang; Linda L D Zhong; Chen-Yuan Lin; Ling Zhao; Zi-Wan Ning; Dong-Dong Hu; Man Zhang; Ke Tian; Chung-Wah Cheng; Zhao-Xiang Bian Journal: Chin Med Date: 2018-03-21 Impact factor: 5.455