Literature DB >> 22735503

Promising therapies for treating and/or preventing androgenic alopecia.

K J McElwee1, J S Shapiro.   

Abstract

Androgenetic alopecia (AGA) may affect up to 70% of men and 40% of women at some point in their lifetime. While men typically present with a distinctive alopecia pattern involving hairline recession and vertex balding, women normally exhibit a diffuse hair thinning over the top of their scalps. The treatment standard in dermatology clinics continues to be minoxidil and finasteride with hair transplantation as a surgical option. Here we briefly review current therapeutic options and treatments under active investigation. Dutasteride and ketoconazole are also employed for AGA, while prostaglandin analogues latanoprost and bimatoprost are being investigated for their hair growth promoting potential. Laser treatment products available for home use and from cosmetic clinics are becoming popular. In the future, new cell mediated treatment approaches may be available for AGA. While there are a number of potential treatment options, good clinical trial data proving hair growth efficacy is limited.

Entities:  

Mesh:

Substances:

Year:  2012        PMID: 22735503

Source DB:  PubMed          Journal:  Skin Therapy Lett        ISSN: 1201-5989


  15 in total

1.  Low-level laser treatment stimulates hair growth via upregulating Wnt10b and β-catenin expression in C3H/HeJ mice.

Authors:  Tiran Zhang; Liqiang Liu; Jincai Fan; Jia Tian; Cheng Gan; Zengjie Yang; Hu Jiao; Bing Han; Zheng Liu
Journal:  Lasers Med Sci       Date:  2017-05-16       Impact factor: 3.161

Review 2.  Efficacy of fractional lasers in treating alopecia: a literature review.

Authors:  Marina Perper; Adam S Aldahan; Rachel A Fayne; Christopher P Emerson; Keyvan Nouri
Journal:  Lasers Med Sci       Date:  2017-08-16       Impact factor: 3.161

3.  The Effect of the Fractional Carbon Dioxide Laser on Improving Minoxidil Delivery for the Treatment of Androgenetic Alopecia.

Authors:  Manal Salah; Nevien Samy; Marwa Mohamed Fawzy; Abdel Razik Farrag; Hany Shehata; Aya Hany
Journal:  J Lasers Med Sci       Date:  2019-01-18

Review 4.  Effectiveness of Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature.

Authors:  Jessica Cervantes; Marina Perper; Lulu L Wong; Ariel E Eber; Alexandra C Villasante Fricke; Tongyu Cao Wikramanayake; Joaquin J Jimenez
Journal:  Skin Appendage Disord       Date:  2017-06-24

5.  The Clinical Efficacy and Safety of Autologous Activated Platelet-Rich Plasma Injection in Androgenetic Alopecia.

Authors:  Niluka Dilrukshi Paththinige; Janaka K W Akarawita; Geetha Jeganathan
Journal:  Skin Appendage Disord       Date:  2019-10-04

6.  Photobiomodulation therapy for hair regeneration: A synergetic activation of β-CATENIN in hair follicle stem cells by ROS and paracrine WNTs.

Authors:  Huan Jin; Zhengzhi Zou; Haocai Chang; Qi Shen; Lingfeng Liu; Da Xing
Journal:  Stem Cell Reports       Date:  2021-05-20       Impact factor: 7.765

7.  Study of platelet-rich plasma injections in the treatment of androgenetic alopecia through an one-year period.

Authors:  Maria-Angeliki Gkini; Alexandros-Efstratios Kouskoukis; Gregory Tripsianis; Dimitris Rigopoulos; Konstantinos Kouskoukis
Journal:  J Cutan Aesthet Surg       Date:  2014 Oct-Dec

8.  Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice.

Authors:  Ramya Lakshmi Rajendran; Prakash Gangadaran; Soon Sun Bak; Ji Min Oh; Senthilkumar Kalimuthu; Ho Won Lee; Se Hwan Baek; Liya Zhu; Young Kwan Sung; Shin Young Jeong; Sang-Woo Lee; Jaetae Lee; Byeong-Cheol Ahn
Journal:  Sci Rep       Date:  2017-11-14       Impact factor: 4.379

9.  Efficacy and safety of a low-level laser device in the treatment of male and female pattern hair loss: a multicenter, randomized, sham device-controlled, double-blind study.

Authors:  Joaquin J Jimenez; Tongyu C Wikramanayake; Wilma Bergfeld; Maria Hordinsky; Janet G Hickman; Michael R Hamblin; Lawrence A Schachner
Journal:  Am J Clin Dermatol       Date:  2014-04       Impact factor: 7.403

Review 10.  Conventional and novel stem cell based therapies for androgenic alopecia.

Authors:  Dodanim Talavera-Adame; Daniella Newman; Nathan Newman
Journal:  Stem Cells Cloning       Date:  2017-08-31
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.