| Literature DB >> 22735454 |
Hironari Nomura1, Teiko Komori, Shuhei Uemura, Yui Kanda, Koji Shimotani, Kana Nakai, Takuya Furuichi, Kohsuke Takebayashi, Takanori Sugimoto, Satoshi Sano, I Nengah Suwastika, Eiichiro Fukusaki, Hirofumi Yoshioka, Yoichi Nakahira, Takashi Shiina.
Abstract
Chloroplasts have a critical role in plant immunity as a site for the production for salicylic acid and jasmonic acid, important mediators of plant immunity. However, the molecular link between chloroplasts and the cytoplasmic-nuclear immune system remains largely unknown. Here we show that pathogen-associated molecular pattern (PAMP) signals are quickly relayed to chloroplasts and evoke specific Ca(2+) signatures in the stroma. We further demonstrate that a chloroplast-localized protein, named calcium-sensing receptor (CAS), is involved in stromal Ca(2+) transients and responsible for both PAMP-induced basal resistance and R gene-mediated hypersensitive cell death. CAS acts upstream of salicylic acid accumulation. Transcriptome analysis demonstrates that CAS is involved in PAMP-induced expression of defence genes and suppression of chloroplast gene expression possibly through (1)O(2)-mediated retrograde signalling, allowing chloroplast-mediated transcriptional reprogramming during plant immune responses. The present study reveals a previously unknown chloroplast-mediated signalling pathway linking chloroplasts to cytoplasmic-nuclear immune responses.Entities:
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Year: 2012 PMID： 22735454 DOI： 10.1038/ncomms1926
Source DB: PubMed Journal: Nat Commun ISSN： 2041-1723 Impact factor: 14.919