Abeer Yasin1, Andréanne Benidir, Guido Filler. 1. Department of Pediatrics, Division of Pediatric Nephrology, Children's Hospital, London Health Science Centre, University of Western Ontario, London ON, Canada.
Abstract
AIMS: To assess the influence of height age and short stature on BMI z-scores in children with chronic kidney disease (CKD) in view of the pandemic increase of childhood obesity. MATERIALS: Pediatric nephrology patients older than 2 years of age from 2 tertiary centers in Ontario and age- and gender matched controls from a local reference population. METHODS: We estimated height, weight and body mass index (BMI) z-scores of 705 nephrology patients (319 female) and 4,196 controls aged 2.01 - 19.92 years with chronological and height-adjusted age (corresponding age for a given height plotted on the 50th percentile). The National Health and Nutrition Examination Survey (NHANES III) was used for the z-score Estimation. RESULTS: Chronological age-based patient weight z-scores were significantly heavier than in the NHANES data (median weight z-score +0.29, BMI z-score +0.51; significantly non-zero), not significantly different from height-adjusted age-based BMI z-score (+0.51). The children with kidney problems were shorter (-0.10 SD) than controls. CONCLUSION: The proportion of overweight nephrology patients was similar to matched controls and BMI z-score diminished with worsening GFR.
AIMS: To assess the influence of height age and short stature on BMI z-scores in children with chronic kidney disease (CKD) in view of the pandemic increase of childhood obesity. MATERIALS: Pediatric nephrologypatients older than 2 years of age from 2 tertiary centers in Ontario and age- and gender matched controls from a local reference population. METHODS: We estimated height, weight and body mass index (BMI) z-scores of 705 nephrology patients (319 female) and 4,196 controls aged 2.01 - 19.92 years with chronological and height-adjusted age (corresponding age for a given height plotted on the 50th percentile). The National Health and Nutrition Examination Survey (NHANES III) was used for the z-score Estimation. RESULTS: Chronological age-based patient weight z-scores were significantly heavier than in the NHANES data (median weight z-score +0.29, BMI z-score +0.51; significantly non-zero), not significantly different from height-adjusted age-based BMI z-score (+0.51). The children with kidney problems were shorter (-0.10 SD) than controls. CONCLUSION: The proportion of overweight nephrologypatients was similar to matched controls and BMI z-score diminished with worsening GFR.
Authors: Franz Schaefer; Laura Benner; Dagmara Borzych-Dużałka; Joshua Zaritsky; Hong Xu; Lesley Rees; Zenaida L Antonio; Erkin Serdaroglu; Nakysa Hooman; Hiren Patel; Lale Sever; Karel Vondrak; Joseph Flynn; Anabella Rébori; William Wong; Tuula Hölttä; Zeynep Yuruk Yildirim; Bruno Ranchin; Ryszard Grenda; Sara Testa; Dorota Drożdz; Attila J Szabo; Loai Eid; Biswanath Basu; Renata Vitkevic; Cynthia Wong; Stephen J Pottoore; Dominik Müller; Ruhan Dusunsel; Claudia Gonzalez Celedon; Marc Fila; Lisa Sartz; Anja Sander; Bradley A Warady Journal: Sci Rep Date: 2019-03-20 Impact factor: 4.379