Literature DB >> 22734942

One-pot multicomponent cascade reaction of N,S-ketene acetal: solvent-free synthesis of imidazo[1,2-a]thiochromeno[3,2-e]pyridines.

Ming Li1, Han Cao, Yong Wang, Xiu-Liang Lv, Li-Rong Wen.   

Abstract

Unprecedented imidazo[1,2-a]thiochromeno[3,2-e]pyridines have been synthesized via a three-component cascade reaction under solvent-free conditions. This one-pot transformation involving multiple steps and not requiring the use of transition n class="Chemical">metal catalysts constructs three new C-C bonds, two C-N bonds, one C-S bond, and three new rings with all reactants efficiently utilized.

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Year:  2012        PMID: 22734942     DOI: 10.1021/ol301441v

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

Review 1.  Catalytic Approaches to Multicomponent Reactions: A Critical Review and Perspectives on the Roles of Catalysis.

Authors:  Brenno A D Neto; Rafael O Rocha; Marcelo O Rodrigues
Journal:  Molecules       Date:  2021-12-27       Impact factor: 4.411

  1 in total

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